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Progestins induce transcriptional activation of signal transducer and activator of transcription 3 (Stat3) via a Jak- and Src-dependent mechanism in breast cancer cells.
Proietti C, Salatino M, Rosemblit C, Carnevale R, Pecci A, Kornblihtt AR, Molinolo AA, Frahm I, Charreau EH, Schillaci R, Elizalde PV. Proietti C, et al. Among authors: frahm i. Mol Cell Biol. 2005 Jun;25(12):4826-40. doi: 10.1128/MCB.25.12.4826-4840.2005. Mol Cell Biol. 2005. PMID: 15923602 Free PMC article.
Inhibition of in vivo breast cancer growth by antisense oligodeoxynucleotides to type I insulin-like growth factor receptor mRNA involves inactivation of ErbBs, PI-3K/Akt and p42/p44 MAPK signaling pathways but not modulation of progesterone receptor activity.
Salatino M, Schillaci R, Proietti CJ, Carnevale R, Frahm I, Molinolo AA, Iribarren A, Charreau EH, Elizalde PV. Salatino M, et al. Among authors: frahm i. Oncogene. 2004 Jul 1;23(30):5161-74. doi: 10.1038/sj.onc.1207659. Oncogene. 2004. PMID: 15122317
Targeting Stat3 induces senescence in tumor cells and elicits prophylactic and therapeutic immune responses against breast cancer growth mediated by NK cells and CD4+ T cells.
Tkach M, Coria L, Rosemblit C, Rivas MA, Proietti CJ, Díaz Flaqué MC, Beguelin W, Frahm I, Charreau EH, Cassataro J, Elizalde PV, Schillaci R. Tkach M, et al. Among authors: frahm i. J Immunol. 2012 Aug 1;189(3):1162-72. doi: 10.4049/jimmunol.1102538. Epub 2012 Jun 29. J Immunol. 2012. PMID: 22753933
Clinical relevance of ErbB-2/HER2 nuclear expression in breast cancer.
Schillaci R, Guzmán P, Cayrol F, Beguelin W, Díaz Flaqué MC, Proietti CJ, Pineda V, Palazzi J, Frahm I, Charreau EH, Maronna E, Roa JC, Elizalde PV. Schillaci R, et al. Among authors: frahm i. BMC Cancer. 2012 Feb 22;12:74. doi: 10.1186/1471-2407-12-74. BMC Cancer. 2012. PMID: 22356700 Free PMC article.
TNFα-Induced Mucin 4 Expression Elicits Trastuzumab Resistance in HER2-Positive Breast Cancer.
Mercogliano MF, De Martino M, Venturutti L, Rivas MA, Proietti CJ, Inurrigarro G, Frahm I, Allemand DH, Deza EG, Ares S, Gercovich FG, Guzmán P, Roa JC, Elizalde PV, Schillaci R. Mercogliano MF, et al. Among authors: frahm i. Clin Cancer Res. 2017 Feb 1;23(3):636-648. doi: 10.1158/1078-0432.CCR-16-0970. Epub 2016 Oct 3. Clin Cancer Res. 2017. PMID: 27698002
Invasive micropapillary carcinoma of the breast overexpresses MUC4 and is associated with poor outcome to adjuvant trastuzumab in HER2-positive breast cancer.
Mercogliano MF, Inurrigarro G, De Martino M, Venturutti L, Rivas MA, Cordo-Russo R, Proietti CJ, Fernández EA, Frahm I, Barchuk S, Allemand DH, Figurelli S, Deza EG, Ares S, Gercovich FG, Cortese E, Amasino M, Guzmán P, Roa JC, Elizalde PV, Schillaci R. Mercogliano MF, et al. Among authors: frahm i. BMC Cancer. 2017 Dec 28;17(1):895. doi: 10.1186/s12885-017-3897-x. BMC Cancer. 2017. PMID: 29281999 Free PMC article.
A phase II dose-escalation trial of perioperative desmopressin (1-desamino-8-d-arginine vasopressin) in breast cancer patients.
Weinberg RS, Grecco MO, Ferro GS, Seigelshifer DJ, Perroni NV, Terrier FJ, Sánchez-Luceros A, Maronna E, Sánchez-Marull R, Frahm I, Guthmann MD, Di Leo D, Spitzer E, Ciccia GN, Garona J, Pifano M, Torbidoni AV, Gomez DE, Ripoll GV, Gomez RE, Demarco IA, Alonso DF. Weinberg RS, et al. Among authors: frahm i. Springerplus. 2015 Aug 19;4:428. doi: 10.1186/s40064-015-1217-y. eCollection 2015. Springerplus. 2015. PMID: 26306290 Free PMC article.
20 results