Wofford JA - Search Results

1

An essential role for an inositol polyphosphate multikinase, Ipk2, in mouse embryogenesis and second messenger production.

Frederick JP, Mattiske D, Wofford JA, Megosh LC, Drake LY, Chiou ST, Hogan BL, York JD. Frederick JP, et al. Among authors: wofford ja. Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8454-9. doi: 10.1073/pnas.0503706102. Epub 2005 Jun 6. Proc Natl Acad Sci U S A. 2005. PMID: 15939867 Free PMC article.

2

Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation.

Juntilla MM, Wofford JA, Birnbaum MJ, Rathmell JC, Koretzky GA. Juntilla MM, et al. Among authors: wofford ja. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12105-10. doi: 10.1073/pnas.0705285104. Epub 2007 Jul 3. Proc Natl Acad Sci U S A. 2007. PMID: 17609365 Free PMC article.

3

Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1.

Zhao Y, Altman BJ, Coloff JL, Herman CE, Jacobs SR, Wieman HL, Wofford JA, Dimascio LN, Ilkayeva O, Kelekar A, Reya T, Rathmell JC. Zhao Y, et al. Among authors: wofford ja. Mol Cell Biol. 2007 Jun;27(12):4328-39. doi: 10.1128/MCB.00153-07. Epub 2007 Mar 19. Mol Cell Biol. 2007. PMID: 17371841 Free PMC article.

4

Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways.

Jacobs SR, Herman CE, Maciver NJ, Wofford JA, Wieman HL, Hammen JJ, Rathmell JC. Jacobs SR, et al. Among authors: wofford ja. J Immunol. 2008 Apr 1;180(7):4476-86. doi: 10.4049/jimmunol.180.7.4476. J Immunol. 2008. PMID: 18354169 Free PMC article.

5

Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells.

Coloff JL, Mason EF, Altman BJ, Gerriets VA, Liu T, Nichols AN, Zhao Y, Wofford JA, Jacobs SR, Ilkayeva O, Garrison SP, Zambetti GP, Rathmell JC. Coloff JL, et al. Among authors: wofford ja. J Biol Chem. 2011 Feb 18;286(7):5921-33. doi: 10.1074/jbc.M110.179101. Epub 2010 Dec 15. J Biol Chem. 2011. PMID: 21159778 Free PMC article.

6

IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival.

Wofford JA, Wieman HL, Jacobs SR, Zhao Y, Rathmell JC. Wofford JA, et al. Blood. 2008 Feb 15;111(4):2101-11. doi: 10.1182/blood-2007-06-096297. Epub 2007 Nov 27. Blood. 2008. PMID: 18042802 Free PMC article.

7

Surfactant protein A differentially regulates peripheral and inflammatory neutrophil chemotaxis.

Schagat TL, Wofford JA, Greene KE, Wright JR. Schagat TL, et al. Among authors: wofford ja. Am J Physiol Lung Cell Mol Physiol. 2003 Jan;284(1):L140-7. doi: 10.1152/ajplung.00125.2002. Epub 2002 Aug 30. Am J Physiol Lung Cell Mol Physiol. 2003. PMID: 12388367 Free article.

8

Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival.

Maciver NJ, Jacobs SR, Wieman HL, Wofford JA, Coloff JL, Rathmell JC. Maciver NJ, et al. Among authors: wofford ja. J Leukoc Biol. 2008 Oct;84(4):949-57. doi: 10.1189/jlb.0108024. Epub 2008 Jun 24. J Leukoc Biol. 2008. PMID: 18577716 Free PMC article. Review.

9

Autophagy provides nutrients but can lead to Chop-dependent induction of Bim to sensitize growth factor-deprived cells to apoptosis.

Altman BJ, Wofford JA, Zhao Y, Coloff JL, Ferguson EC, Wieman HL, Day AE, Ilkayeva O, Rathmell JC. Altman BJ, et al. Among authors: wofford ja. Mol Biol Cell. 2009 Feb;20(4):1180-91. doi: 10.1091/mbc.e08-08-0829. Epub 2008 Dec 24. Mol Biol Cell. 2009. PMID: 19109422 Free PMC article.

10

Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking.

Wieman HL, Wofford JA, Rathmell JC. Wieman HL, et al. Among authors: wofford ja. Mol Biol Cell. 2007 Apr;18(4):1437-46. doi: 10.1091/mbc.e06-07-0593. Epub 2007 Feb 14. Mol Biol Cell. 2007. PMID: 17301289 Free PMC article.

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