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Drug targeting Mycobacterium tuberculosis cell wall synthesis: genetics of dTDP-rhamnose synthetic enzymes and development of a microtiter plate-based screen for inhibitors of conversion of dTDP-glucose to dTDP-rhamnose.
Ma Y, Stern RJ, Scherman MS, Vissa VD, Yan W, Jones VC, Zhang F, Franzblau SG, Lewis WH, McNeil MR. Ma Y, et al. Among authors: jones vc. Antimicrob Agents Chemother. 2001 May;45(5):1407-16. doi: 10.1128/AAC.45.5.1407-1416.2001. Antimicrob Agents Chemother. 2001. PMID: 11302803 Free PMC article.
Expression, essentiality, and a microtiter plate assay for mycobacterial GlmU, the bifunctional glucosamine-1-phosphate acetyltransferase and N-acetylglucosamine-1-phosphate uridyltransferase.
Zhang W, Jones VC, Scherman MS, Mahapatra S, Crick D, Bhamidi S, Xin Y, McNeil MR, Ma Y. Zhang W, et al. Among authors: jones vc. Int J Biochem Cell Biol. 2008;40(11):2560-71. doi: 10.1016/j.biocel.2008.05.003. Epub 2008 May 15. Int J Biochem Cell Biol. 2008. PMID: 18573680 Free PMC article.
The structure-activity relationship of urea derivatives as anti-tuberculosis agents.
Brown JR, North EJ, Hurdle JG, Morisseau C, Scarborough JS, Sun D, Korduláková J, Scherman MS, Jones V, Grzegorzewicz A, Crew RM, Jackson M, McNeil MR, Lee RE. Brown JR, et al. Bioorg Med Chem. 2011 Sep 15;19(18):5585-95. doi: 10.1016/j.bmc.2011.07.034. Epub 2011 Jul 24. Bioorg Med Chem. 2011. PMID: 21840723 Free PMC article.
Screening a library of 1600 adamantyl ureas for anti-Mycobacterium tuberculosis activity in vitro and for better physical chemical properties for bioavailability.
Scherman MS, North EJ, Jones V, Hess TN, Grzegorzewicz AE, Kasagami T, Kim IH, Merzlikin O, Lenaerts AJ, Lee RE, Jackson M, Morisseau C, McNeil MR. Scherman MS, et al. Bioorg Med Chem. 2012 May 15;20(10):3255-62. doi: 10.1016/j.bmc.2012.03.058. Epub 2012 Mar 31. Bioorg Med Chem. 2012. PMID: 22522007 Free PMC article.
95 results