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Ageing and metabolism: drug discovery opportunities.
Curtis R, Geesaman BJ, DiStefano PS. Curtis R, et al. Among authors: distefano ps. Nat Rev Drug Discov. 2005 Jul;4(7):569-80. doi: 10.1038/nrd1777. Nat Rev Drug Discov. 2005. PMID: 15976816 Review.
Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1.
Napper AD, Hixon J, McDonagh T, Keavey K, Pons JF, Barker J, Yau WT, Amouzegh P, Flegg A, Hamelin E, Thomas RJ, Kates M, Jones S, Navia MA, Saunders JO, DiStefano PS, Curtis R. Napper AD, et al. Among authors: distefano ps. J Med Chem. 2005 Dec 15;48(25):8045-54. doi: 10.1021/jm050522v. J Med Chem. 2005. PMID: 16335928
Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity.
Longo KA, Govek EK, Nolan A, McDonagh T, Charoenthongtrakul S, Giuliana DJ, Morgan K, Hixon J, Zhou C, Kelder B, Kopchick JJ, Saunders JO, Navia MA, Curtis R, DiStefano PS, Geddes BJ. Longo KA, et al. Among authors: distefano ps. J Pharmacol Exp Ther. 2011 Oct;339(1):115-24. doi: 10.1124/jpet.111.183764. Epub 2011 Jul 20. J Pharmacol Exp Ther. 2011. PMID: 21775475
104 results