Regulation of channel gating by AMP-activated protein kinase modulates cystic fibrosis transmembrane conductance regulator activity in lung submucosal cells.
Hallows KR, McCane JE, Kemp BE, Witters LA, Foskett JK.
Hallows KR, et al. Among authors: kemp be.
J Biol Chem. 2003 Jan 10;278(2):998-1004. doi: 10.1074/jbc.M210621200. Epub 2002 Nov 8.
J Biol Chem. 2003.
PMID: 12427743
Free article.
The metabolic sensor AMP-activated kinase (AMPK) binds to and phosphorylates CFTR, co-localizes with it in various tissues, and inhibits CFTR currents in Xenopus oocytes (Hallows, K. R., Raghuram, V., Kemp, B. E., Witters, L. A. & Foskett, J. K. (2000) J. Clin. Invest. …
The metabolic sensor AMP-activated kinase (AMPK) binds to and phosphorylates CFTR, co-localizes with it in various tissues, and inhibits CFT …