Cadiñanos J - Search Results

1

Genomic instability in laminopathy-based premature aging.

Liu B, Wang J, Chan KM, Tjia WM, Deng W, Guan X, Huang JD, Li KM, Chau PY, Chen DJ, Pei D, Pendas AM, Cadiñanos J, López-Otín C, Tse HF, Hutchison C, Chen J, Cao Y, Cheah KS, Tryggvason K, Zhou Z. Liu B, et al. Among authors: cadinanos j. Nat Med. 2005 Jul;11(7):780-5. doi: 10.1038/nm1266. Epub 2005 Jun 26. Nat Med. 2005. PMID: 15980864

2

Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice.

Pendás AM, Zhou Z, Cadiñanos J, Freije JM, Wang J, Hultenby K, Astudillo A, Wernerson A, Rodríguez F, Tryggvason K, López-Otín C. Pendás AM, et al. Among authors: cadinanos j. Nat Genet. 2002 May;31(1):94-9. doi: 10.1038/ng871. Epub 2002 Apr 1. Nat Genet. 2002. PMID: 11923874

3

Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation.

Varela I, Cadiñanos J, Pendás AM, Gutiérrez-Fernández A, Folgueras AR, Sánchez LM, Zhou Z, Rodríguez FJ, Stewart CL, Vega JA, Tryggvason K, Freije JM, López-Otín C. Varela I, et al. Among authors: cadinanos j. Nature. 2005 Sep 22;437(7058):564-8. doi: 10.1038/nature04019. Epub 2005 Aug 3. Nature. 2005. PMID: 16079796

4

From immature lamin to premature aging: molecular pathways and therapeutic opportunities.

Cadiñanos J, Varela I, López-Otín C, Freije JM. Cadiñanos J, et al. Cell Cycle. 2005 Dec;4(12):1732-5. doi: 10.4161/cc.4.12.2202. Epub 2005 Dec 23. Cell Cycle. 2005. PMID: 16258283

5

Nuclear envelope defects cause stem cell dysfunction in premature-aging mice.

Espada J, Varela I, Flores I, Ugalde AP, Cadiñanos J, Pendás AM, Stewart CL, Tryggvason K, Blasco MA, Freije JM, López-Otín C. Espada J, et al. Among authors: cadinanos j. J Cell Biol. 2008 Apr 7;181(1):27-35. doi: 10.1083/jcb.200801096. Epub 2008 Mar 31. J Cell Biol. 2008. PMID: 18378773 Free PMC article.

6

Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging.

Varela I, Pereira S, Ugalde AP, Navarro CL, Suárez MF, Cau P, Cadiñanos J, Osorio FG, Foray N, Cobo J, de Carlos F, Lévy N, Freije JM, López-Otín C. Varela I, et al. Among authors: cadinanos j. Nat Med. 2008 Jul;14(7):767-72. doi: 10.1038/nm1786. Epub 2008 Jun 29. Nat Med. 2008. PMID: 18587406

7

Prelamin A causes progeria through cell-extrinsic mechanisms and prevents cancer invasion.

de la Rosa J, Freije JM, Cabanillas R, Osorio FG, Fraga MF, Fernández-García MS, Rad R, Fanjul V, Ugalde AP, Liang Q, Prosser HM, Bradley A, Cadiñanos J, López-Otín C. de la Rosa J, et al. Among authors: cadinanos j. Nat Commun. 2013;4:2268. doi: 10.1038/ncomms3268. Nat Commun. 2013. PMID: 23917225 Free PMC article.

8

Premature aging in mice activates a systemic metabolic response involving autophagy induction.

Mariño G, Ugalde AP, Salvador-Montoliu N, Varela I, Quirós PM, Cadiñanos J, van der Pluijm I, Freije JM, López-Otín C. Mariño G, et al. Among authors: cadinanos j. Hum Mol Genet. 2008 Jul 15;17(14):2196-211. doi: 10.1093/hmg/ddn120. Epub 2008 Apr 28. Hum Mol Genet. 2008. PMID: 18443001

9

Aging and chronic DNA damage response activate a regulatory pathway involving miR-29 and p53.

Ugalde AP, Ramsay AJ, de la Rosa J, Varela I, Mariño G, Cadiñanos J, Lu J, Freije JM, López-Otín C. Ugalde AP, et al. Among authors: cadinanos j. EMBO J. 2011 Jun 1;30(11):2219-32. doi: 10.1038/emboj.2011.124. Epub 2011 Apr 26. EMBO J. 2011. PMID: 21522133 Free PMC article.

10

Splicing-directed therapy in a new mouse model of human accelerated aging.

Osorio FG, Navarro CL, Cadiñanos J, López-Mejía IC, Quirós PM, Bartoli C, Rivera J, Tazi J, Guzmán G, Varela I, Depetris D, de Carlos F, Cobo J, Andrés V, De Sandre-Giovannoli A, Freije JM, Lévy N, López-Otín C. Osorio FG, et al. Among authors: cadinanos j. Sci Transl Med. 2011 Oct 26;3(106):106ra107. doi: 10.1126/scitranslmed.3002847. Sci Transl Med. 2011. PMID: 22030750

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