Higgins CF - Search Results

1

Expression of RPIP9 (Rap2 interacting protein 9) is activated in breast carcinoma and correlates with a poor prognosis.

Raguz S, De Bella MT, Slade MJ, Higgins CF, Coombes RC, Yagüe E. Raguz S, et al. Among authors: higgins cf. Int J Cancer. 2005 Dec 20;117(6):934-41. doi: 10.1002/ijc.21252. Int J Cancer. 2005. PMID: 15986426

2

Production of P-glycoprotein from the MDR1 upstream promoter is insufficient to affect the response to first-line chemotherapy in advanced breast cancer.

Raguz S, Randle RA, Sharpe ER, Foekens JA, Sieuwerts AM, Meijer-van Gelder ME, Melo JV, Higgins CF, Yagüe E. Raguz S, et al. Among authors: higgins cf. Int J Cancer. 2008 Mar 1;122(5):1058-67. doi: 10.1002/ijc.23149. Int J Cancer. 2008. PMID: 17955490

3

Activation of the MDR1 upstream promoter in breast carcinoma as a surrogate for metastatic invasion.

Raguz S, Tamburo De Bella M, Tripuraneni G, Slade MJ, Higgins CF, Coombes RC, Yagüe E. Raguz S, et al. Among authors: higgins cf. Clin Cancer Res. 2004 Apr 15;10(8):2776-83. doi: 10.1158/1078-0432.ccr-03-0517. Clin Cancer Res. 2004. PMID: 15102684

4

P-glycoprotein (MDR1) expression in leukemic cells is regulated at two distinct steps, mRNA stabilization and translational initiation.

Yague E, Armesilla AL, Harrison G, Elliott J, Sardini A, Higgins CF, Raguz S. Yague E, et al. Among authors: higgins cf. J Biol Chem. 2003 Mar 21;278(12):10344-52. doi: 10.1074/jbc.M211093200. Epub 2003 Jan 13. J Biol Chem. 2003. PMID: 12525496 Free article.

5

Ability to acquire drug resistance arises early during the tumorigenesis process.

Yagüe E, Arance A, Kubitza L, O'Hare M, Jat P, Ogilvie CM, Hart IR, Higgins CF, Raguz S. Yagüe E, et al. Among authors: higgins cf. Cancer Res. 2007 Feb 1;67(3):1130-7. doi: 10.1158/0008-5472.CAN-06-2574. Cancer Res. 2007. PMID: 17283147 Free article.

6

Role of the highly structured 5'-end region of MDR1 mRNA in P-glycoprotein expression.

Randle RA, Raguz S, Higgins CF, Yagüe E. Randle RA, et al. Among authors: higgins cf. Biochem J. 2007 Sep 15;406(3):445-55. doi: 10.1042/BJ20070235. Biochem J. 2007. PMID: 17573715 Free PMC article.

7

Complete reversal of multidrug resistance by stable expression of small interfering RNAs targeting MDR1.

Yagüe E, Higgins CF, Raguz S. Yagüe E, et al. Among authors: higgins cf. Gene Ther. 2004 Jul;11(14):1170-4. doi: 10.1038/sj.gt.3302269. Gene Ther. 2004. PMID: 15164094

8

Multidrug transporter activity in lymphocytes.

Elliott JI, Raguz S, Higgins CF. Elliott JI, et al. Among authors: higgins cf. Br J Pharmacol. 2004 Dec;143(7):899-907. doi: 10.1038/sj.bjp.0705940. Epub 2004 Oct 18. Br J Pharmacol. 2004. PMID: 15492020 Free PMC article.

9

mRNA escape from stress granule sequestration is dictated by localization to the endoplasmic reticulum.

Unsworth H, Raguz S, Edwards HJ, Higgins CF, Yagüe E. Unsworth H, et al. Among authors: higgins cf. FASEB J. 2010 Sep;24(9):3370-80. doi: 10.1096/fj.09-151142. Epub 2010 May 7. FASEB J. 2010. PMID: 20453113 Free article.

10

Human ClC-3 is not the swelling-activated chloride channel involved in cell volume regulation.

Weylandt KH, Valverde MA, Nobles M, Raguz S, Amey JS, Diaz M, Nastrucci C, Higgins CF, Sardini A. Weylandt KH, et al. Among authors: higgins cf. J Biol Chem. 2001 May 18;276(20):17461-7. doi: 10.1074/jbc.M011667200. Epub 2001 Feb 22. J Biol Chem. 2001. PMID: 11278960 Free article.

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