Lenz DH - Search Results

1

Second generation transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase.

Evans GB, Furneaux RH, Lenz DH, Painter GF, Schramm VL, Singh V, Tyler PC. Evans GB, et al. Among authors: lenz dh. J Med Chem. 2005 Jul 14;48(14):4679-89. doi: 10.1021/jm050269z. J Med Chem. 2005. PMID: 16000004

2

Energetic mapping of transition state analogue interactions with human and Plasmodium falciparum purine nucleoside phosphorylases.

Lewandowicz A, Ringia EA, Ting LM, Kim K, Tyler PC, Evans GB, Zubkova OV, Mee S, Painter GF, Lenz DH, Furneaux RH, Schramm VL. Lewandowicz A, et al. Among authors: lenz dh. J Biol Chem. 2005 Aug 26;280(34):30320-8. doi: 10.1074/jbc.M505033200. Epub 2005 Jun 16. J Biol Chem. 2005. PMID: 15961383 Free article.

3

Syntheses and bio-activities of the L-enantiomers of two potent transition state analogue inhibitors of purine nucleoside phosphorylases.

Clinch K, Evans GB, Fleet GW, Furneaux RH, Johnson SW, Lenz DH, Mee SP, Rands PR, Schramm VL, Taylor Ringia EA, Tyler PC. Clinch K, et al. Among authors: lenz dh. Org Biomol Chem. 2006 Mar 21;4(6):1131-9. doi: 10.1039/b517883e. Epub 2006 Jan 26. Org Biomol Chem. 2006. PMID: 16525558

4

A practical synthesis of (3R,4R)-N-tert-butoxycarbonyl-4-hydroxymethylpyrrolidin-3-ol.

Clinch K, Evans GB, Furneaux RH, Lenz DH, Mason JM, Mee SP, Tyler PC, Wilcox SJ. Clinch K, et al. Among authors: lenz dh. Org Biomol Chem. 2007 Sep 7;5(17):2800-2. doi: 10.1039/b708796a. Epub 2007 Jul 20. Org Biomol Chem. 2007. PMID: 17700848

5

Femtomolar transition state analogue inhibitors of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Escherichia coli.

Singh V, Evans GB, Lenz DH, Mason JM, Clinch K, Mee S, Painter GF, Tyler PC, Furneaux RH, Lee JE, Howell PL, Schramm VL. Singh V, et al. Among authors: lenz dh. J Biol Chem. 2005 May 6;280(18):18265-73. doi: 10.1074/jbc.M414472200. Epub 2005 Mar 4. J Biol Chem. 2005. PMID: 15749708 Free article.

6

Picomolar inhibitors as transition-state probes of 5'-methylthioadenosine nucleosidases.

Gutierrez JA, Luo M, Singh V, Li L, Brown RL, Norris GE, Evans GB, Furneaux RH, Tyler PC, Painter GF, Lenz DH, Schramm VL. Gutierrez JA, et al. Among authors: lenz dh. ACS Chem Biol. 2007 Nov 20;2(11):725-34. doi: 10.1021/cb700166z. ACS Chem Biol. 2007. PMID: 18030989

7

Structure and inhibition of a quorum sensing target from Streptococcus pneumoniae.

Singh V, Shi W, Almo SC, Evans GB, Furneaux RH, Tyler PC, Painter GF, Lenz DH, Mee S, Zheng R, Schramm VL. Singh V, et al. Among authors: lenz dh. Biochemistry. 2006 Oct 31;45(43):12929-41. doi: 10.1021/bi061184i. Biochemistry. 2006. PMID: 17059210 Free PMC article.

8

Studies on the structure and regulation of the human hepatic interleukin-6 receptor.

Rose-John S, Schooltink H, Lenz D, Hipp E, Dufhues G, Schmitz H, Schiel X, Hirano T, Kishimoto T, Heinrich PC. Rose-John S, et al. Eur J Biochem. 1990 May 31;190(1):79-83. doi: 10.1111/j.1432-1033.1990.tb15548.x. Eur J Biochem. 1990. PMID: 2163835 Free article.

9

Structural and functional studies on the human interleukin-6 receptor. Binding, cross-linking, internalization, and degradation of interleukin-6 by fibroblasts transfected with human interleukin-6-receptor cDNA.

Rose-John S, Hipp E, Lenz D, Legrés LG, Korr H, Hirano T, Kishimoto T, Heinrich PC. Rose-John S, et al. J Biol Chem. 1991 Feb 25;266(6):3841-6. J Biol Chem. 1991. PMID: 1995637 Free article.

10

Structural and functional studies on the human hepatic interleukin-6 receptor. Molecular cloning and overexpression in HepG2 cells.

Schooltink H, Stoyan T, Lenz D, Schmitz H, Hirano T, Kishimoto T, Heinrich PC, Rose-John S. Schooltink H, et al. Biochem J. 1991 Aug 1;277 ( Pt 3)(Pt 3):659-64. doi: 10.1042/bj2770659. Biochem J. 1991. PMID: 1872801 Free PMC article.

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