Hutton M - Search Results

1

Tau suppression in a neurodegenerative mouse model improves memory function.

Santacruz K, Lewis J, Spires T, Paulson J, Kotilinek L, Ingelsson M, Guimaraes A, DeTure M, Ramsden M, McGowan E, Forster C, Yue M, Orne J, Janus C, Mariash A, Kuskowski M, Hyman B, Hutton M, Ashe KH. Santacruz K, et al. Among authors: hutton m. Science. 2005 Jul 15;309(5733):476-81. doi: 10.1126/science.1113694. Science. 2005. PMID: 16020737 Free PMC article.

2

Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L).

Ramsden M, Kotilinek L, Forster C, Paulson J, McGowan E, SantaCruz K, Guimaraes A, Yue M, Lewis J, Carlson G, Hutton M, Ashe KH. Ramsden M, et al. Among authors: hutton m. J Neurosci. 2005 Nov 16;25(46):10637-47. doi: 10.1523/JNEUROSCI.3279-05.2005. J Neurosci. 2005. PMID: 16291936 Free PMC article.

3

Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles.

Wittmann CW, Wszolek MF, Shulman JM, Salvaterra PM, Lewis J, Hutton M, Feany MB. Wittmann CW, et al. Among authors: hutton m. Science. 2001 Jul 27;293(5530):711-4. doi: 10.1126/science.1062382. Epub 2001 Jun 14. Science. 2001. PMID: 11408621

4

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

Lewis J, Dickson DW, Lin WL, Chisholm L, Corral A, Jones G, Yen SH, Sahara N, Skipper L, Yager D, Eckman C, Hardy J, Hutton M, McGowan E. Lewis J, et al. Among authors: hutton m. Science. 2001 Aug 24;293(5534):1487-91. doi: 10.1126/science.1058189. Science. 2001. PMID: 11520987

5

Accumulation of pathological tau species and memory loss in a conditional model of tauopathy.

Berger Z, Roder H, Hanna A, Carlson A, Rangachari V, Yue M, Wszolek Z, Ashe K, Knight J, Dickson D, Andorfer C, Rosenberry TL, Lewis J, Hutton M, Janus C. Berger Z, et al. Among authors: hutton m. J Neurosci. 2007 Apr 4;27(14):3650-62. doi: 10.1523/JNEUROSCI.0587-07.2007. J Neurosci. 2007. PMID: 17409229 Free PMC article.

6

Clearing tau pathology with Abeta immunotherapy--reversible and irreversible stages revealed.

Hutton M, McGowan E. Hutton M, et al. Neuron. 2004 Aug 5;43(3):293-4. doi: 10.1016/j.neuron.2004.07.023. Neuron. 2004. PMID: 15294135 Free article. Review.

7

Assembly of tau in transgenic animals expressing P301L tau: alteration of phosphorylation and solubility.

Sahara N, Lewis J, DeTure M, McGowan E, Dickson DW, Hutton M, Yen SH. Sahara N, et al. Among authors: hutton m. J Neurochem. 2002 Dec;83(6):1498-508. doi: 10.1046/j.1471-4159.2002.01241.x. J Neurochem. 2002. PMID: 12472903 Free article.

8

Analysis of tauopathies with transgenic mice.

Hutton M, Lewis J, Dickson D, Yen SH, McGowan E. Hutton M, et al. Trends Mol Med. 2001 Oct;7(10):467-70. doi: 10.1016/s1471-4914(01)02123-2. Trends Mol Med. 2001. PMID: 11597522 Review.

9

The molecular genetics of the tauopathies.

van Slegtenhorst M, Lewis J, Hutton M. van Slegtenhorst M, et al. Among authors: hutton m. Exp Gerontol. 2000 Jul;35(4):461-71. doi: 10.1016/s0531-5565(00)00114-5. Exp Gerontol. 2000. PMID: 10959034 Review.

10

Multi-metric behavioral comparison of APPsw and P301L models for Alzheimer's disease: linkage of poorer cognitive performance to tau pathology in forebrain.

Arendash GW, Lewis J, Leighty RE, McGowan E, Cracchiolo JR, Hutton M, Garcia MF. Arendash GW, et al. Among authors: hutton m. Brain Res. 2004 Jun 25;1012(1-2):29-41. doi: 10.1016/j.brainres.2004.02.081. Brain Res. 2004. PMID: 15158158

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