Kyewski B - Search Results

1

Expression of a natural tumor antigen by thymic epithelial cells impairs the tumor-protective CD4+ T-cell repertoire.

Bos R, van Duikeren S, van Hall T, Kaaijk P, Taubert R, Kyewski B, Klein L, Melief CJ, Offringa R. Bos R, et al. Among authors: kyewski b. Cancer Res. 2005 Jul 15;65(14):6443-9. doi: 10.1158/0008-5472.CAN-05-0666. Cancer Res. 2005. PMID: 16024649

2

A central role for central tolerance.

Kyewski B, Klein L. Kyewski B, et al. Annu Rev Immunol. 2006;24:571-606. doi: 10.1146/annurev.immunol.23.021704.115601. Annu Rev Immunol. 2006. PMID: 16551260 Review.

3

Highly variable expression of tissue-restricted self-antigens in human thymus: implications for self-tolerance and autoimmunity.

Taubert R, Schwendemann J, Kyewski B. Taubert R, et al. Among authors: kyewski b. Eur J Immunol. 2007 Mar;37(3):838-48. doi: 10.1002/eji.200636962. Eur J Immunol. 2007. PMID: 17323415 Free article.

4

Sampling of complementing self-antigen pools by thymic stromal cells maximizes the scope of central T cell tolerance.

Klein L, Roettinger B, Kyewski B. Klein L, et al. Among authors: kyewski b. Eur J Immunol. 2001 Aug;31(8):2476-86. doi: 10.1002/1521-4141(200108)31:8<2476::aid-immu2476>3.0.co;2-t. Eur J Immunol. 2001. PMID: 11500832 Free article.

5

Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self.

Derbinski J, Schulte A, Kyewski B, Klein L. Derbinski J, et al. Among authors: kyewski b. Nat Immunol. 2001 Nov;2(11):1032-9. doi: 10.1038/ni723. Nat Immunol. 2001. PMID: 11600886

6

CD4 T cell tolerance to human C-reactive protein, an inducible serum protein, is mediated by medullary thymic epithelium.

Klein L, Klein T, Rüther U, Kyewski B. Klein L, et al. Among authors: kyewski b. J Exp Med. 1998 Jul 6;188(1):5-16. doi: 10.1084/jem.188.1.5. J Exp Med. 1998. PMID: 9653079 Free PMC article.

7

Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells.

Klein L, Klugmann M, Nave KA, Tuohy VK, Kyewski B. Klein L, et al. Among authors: kyewski b. Nat Med. 2000 Jan;6(1):56-61. doi: 10.1038/71540. Nat Med. 2000. PMID: 10613824

8

Self-antigen presentation by thymic stromal cells: a subtle division of labor.

Klein L, Kyewski B. Klein L, et al. Among authors: kyewski b. Curr Opin Immunol. 2000 Apr;12(2):179-86. doi: 10.1016/s0952-7915(99)00069-2. Curr Opin Immunol. 2000. PMID: 10712940 Review.

9

Making central T-cell tolerance efficient: thymic stromal cells sample distinct self-antigen pools.

Kyewski B, Röttinger B, Klein L. Kyewski B, et al. Curr Top Microbiol Immunol. 2000;251:139-45. doi: 10.1007/978-3-642-57276-0_18. Curr Top Microbiol Immunol. 2000. PMID: 11036769 No abstract available.

10

"Promiscuous" expression of tissue antigens in the thymus: a key to T-cell tolerance and autoimmunity?

Klein L, Kyewski B. Klein L, et al. Among authors: kyewski b. J Mol Med (Berl). 2000;78(9):483-94. doi: 10.1007/s001090000146. J Mol Med (Berl). 2000. PMID: 11140374 Review.

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