Teesdale-Spittle P - Search Results

1

Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation.

Bordeleau ME, Matthews J, Wojnar JM, Lindqvist L, Novac O, Jankowsky E, Sonenberg N, Northcote P, Teesdale-Spittle P, Pelletier J. Bordeleau ME, et al. Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10460-5. doi: 10.1073/pnas.0504249102. Epub 2005 Jul 19. Proc Natl Acad Sci U S A. 2005. PMID: 16030146 Free PMC article.

2

Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A.

Naineni SK, Liang J, Hull K, Cencic R, Zhu M, Northcote P, Teesdale-Spittle P, Romo D, Nagar B, Pelletier J. Naineni SK, et al. Among authors: teesdale spittle p. Cell Chem Biol. 2021 Jun 17;28(6):825-834.e6. doi: 10.1016/j.chembiol.2020.12.006. Epub 2021 Jan 6. Cell Chem Biol. 2021. PMID: 33412110 Free PMC article.

3

The cellular target specificity of pateamine A.

Matthews JH, Maass DR, Northcote PT, Atkinson PH, Teesdale-Spittle PH. Matthews JH, et al. Z Naturforsch C J Biosci. 2013 Sep-Oct;68(9-10):406-15. doi: 10.1515/znc-2013-9-1008. Z Naturforsch C J Biosci. 2013. PMID: 24459774 Free article.

4

The protein synthesis inhibitors mycalamides A and E have limited susceptibility toward the drug efflux network.

Venturi V, Davies C, Singh AJ, Matthews JH, Bellows DS, Northcote PT, Keyzers RA, Teesdale-Spittle PH. Venturi V, et al. J Biochem Mol Toxicol. 2012 Mar;26(3):94-100. doi: 10.1002/jbt.20414. Epub 2011 Dec 8. J Biochem Mol Toxicol. 2012. PMID: 22162108

5

Peloruside A does not bind to the taxoid site on beta-tubulin and retains its activity in multidrug-resistant cell lines.

Gaitanos TN, Buey RM, Díaz JF, Northcote PT, Teesdale-Spittle P, Andreu JM, Miller JH. Gaitanos TN, et al. Cancer Res. 2004 Aug 1;64(15):5063-7. doi: 10.1158/0008-5472.CAN-04-0771. Cancer Res. 2004. PMID: 15289305

6

βI-tubulin mutations in the laulimalide/peloruside binding site mediate drug sensitivity by altering drug-tubulin interactions and microtubule stability.

Kanakkanthara A, Rowe MR, Field JJ, Northcote PT, Teesdale-Spittle PH, Miller JH. Kanakkanthara A, et al. Cancer Lett. 2015 Sep 1;365(2):251-60. doi: 10.1016/j.canlet.2015.06.001. Epub 2015 Jun 4. Cancer Lett. 2015. PMID: 26052091

7

Characterizing the laulimalide-peloruside binding site using site-directed mutagenesis of TUB2 in S. cerevisiae.

Hanna R, Maass DR, Atkinson PH, Northcote PT, Teesdale-Spittle PH, Bellows DS, Miller JH. Hanna R, et al. Mol Biosyst. 2014 Jan;10(1):110-6. doi: 10.1039/c3mb70380k. Mol Biosyst. 2014. PMID: 24161989

8

Heptanosides from galactose-derived oxepenes via stereoselective addition reactions.

Batchelor R, Harvey JE, Northcote PT, Teesdale-Spittle P, Hoberg JO. Batchelor R, et al. J Org Chem. 2009 Oct 16;74(20):7627-32. doi: 10.1021/jo901706e. J Org Chem. 2009. PMID: 19754106

9

Structure-activity studies of the pelorusides: new congeners and semi-synthetic analogues.

Singh AJ, Razzak M, Teesdale-Spittle P, Gaitanos TN, Wilmes A, Paterson I, Goodman JM, Miller JH, Northcote PT. Singh AJ, et al. Org Biomol Chem. 2011 Jun 21;9(12):4456-66. doi: 10.1039/c0ob01127d. Epub 2011 Apr 21. Org Biomol Chem. 2011. PMID: 21512693

10

Characterisation of the biological response of Saccharomyces cerevisiae to the loss of an allele of the eukaryotic initiation factor 4A.

Venturi V, Little R, Bircham PW, Rodigheri Brito J, Atkinson PH, Maass DR, Teesdale-Spittle PH. Venturi V, et al. Biochem Biophys Res Commun. 2018 Feb 19;496(4):1082-1087. doi: 10.1016/j.bbrc.2018.01.137. Epub 2018 Feb 1. Biochem Biophys Res Commun. 2018. PMID: 29397069

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