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Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs.
Morrissey DV, Lockridge JA, Shaw L, Blanchard K, Jensen K, Breen W, Hartsough K, Machemer L, Radka S, Jadhav V, Vaish N, Zinnen S, Vargeese C, Bowman K, Shaffer CS, Jeffs LB, Judge A, MacLachlan I, Polisky B. Morrissey DV, et al. Among authors: zinnen s. Nat Biotechnol. 2005 Aug;23(8):1002-7. doi: 10.1038/nbt1122. Epub 2005 Jul 24. Nat Biotechnol. 2005. PMID: 16041363 Free article.
Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1.
Shen J, Samul R, Silva RL, Akiyama H, Liu H, Saishin Y, Hackett SF, Zinnen S, Kossen K, Fosnaugh K, Vargeese C, Gomez A, Bouhana K, Aitchison R, Pavco P, Campochiaro PA. Shen J, et al. Among authors: zinnen s. Gene Ther. 2006 Feb;13(3):225-34. doi: 10.1038/sj.gt.3302641. Gene Ther. 2006. PMID: 16195704
Bisphosphonate conjugation for bone specific drug targeting.
Farrell KB, Karpeisky A, Thamm DH, Zinnen S. Farrell KB, et al. Among authors: zinnen s. Bone Rep. 2018 Jul 3;9:47-60. doi: 10.1016/j.bonr.2018.06.007. eCollection 2018 Dec. Bone Rep. 2018. PMID: 29992180 Free PMC article. Review.
A promising approach for treatment of tumor-induced bone diseases: utilizing bisphosphonate derivatives of nucleoside antimetabolites.
Reinholz MM, Zinnen SP, Dueck AC, Dingli D, Reinholz GG, Jonart LA, Kitzmann KA, Bruzek AK, Negron V, Abdalla AK, Arendt BK, Croatt AJ, Sanchez-Perez L, Sebesta DP, Lönnberg H, Yoneda T, Nath KA, Jelinek DF, Russell SJ, Ingle JN, Spelsberg TC, Dixon HB, Karpeisky A, Lingle WL. Reinholz MM, et al. Among authors: zinnen sp. Bone. 2010 Jul;47(1):12-22. doi: 10.1016/j.bone.2010.03.006. Epub 2010 Mar 15. Bone. 2010. PMID: 20233612 Free PMC article.
19 results