Giraud AS - Search Results

1

Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling.

Jenkins BJ, Grail D, Nheu T, Najdovska M, Wang B, Waring P, Inglese M, McLoughlin RM, Jones SA, Topley N, Baumann H, Judd LM, Giraud AS, Boussioutas A, Zhu HJ, Ernst M. Jenkins BJ, et al. Among authors: giraud as. Nat Med. 2005 Aug;11(8):845-52. doi: 10.1038/nm1282. Epub 2005 Jul 24. Nat Med. 2005. PMID: 16041381

2

Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice.

Tebbutt NC, Giraud AS, Inglese M, Jenkins B, Waring P, Clay FJ, Malki S, Alderman BM, Grail D, Hollande F, Heath JK, Ernst M. Tebbutt NC, et al. Among authors: giraud as. Nat Med. 2002 Oct;8(10):1089-97. doi: 10.1038/nm763. Epub 2002 Sep 9. Nat Med. 2002. PMID: 12219085

3

Targeting STAT3 in gastric cancer.

Giraud AS, Menheniott TR, Judd LM. Giraud AS, et al. Expert Opin Ther Targets. 2012 Sep;16(9):889-901. doi: 10.1517/14728222.2012.709238. Epub 2012 Jul 26. Expert Opin Ther Targets. 2012. PMID: 22834702 Review.

4

Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130.

Judd LM, Alderman BM, Howlett M, Shulkes A, Dow C, Moverley J, Grail D, Jenkins BJ, Ernst M, Giraud AS. Judd LM, et al. Among authors: giraud as. Gastroenterology. 2004 Jan;126(1):196-207. doi: 10.1053/j.gastro.2003.10.066. Gastroenterology. 2004. PMID: 14699500

5

Differential regulation of gastric tumor growth by cytokines that signal exclusively through the coreceptor gp130.

Howlett M, Judd LM, Jenkins B, La Gruta NL, Grail D, Ernst M, Giraud AS. Howlett M, et al. Among authors: giraud as. Gastroenterology. 2005 Sep;129(3):1005-18. doi: 10.1053/j.gastro.2005.06.068. Gastroenterology. 2005. PMID: 16143138

6

STAT3 activation regulates growth, inflammation, and vascularization in a mouse model of gastric tumorigenesis.

Judd LM, Bredin K, Kalantzis A, Jenkins BJ, Ernst M, Giraud AS. Judd LM, et al. Among authors: giraud as. Gastroenterology. 2006 Oct;131(4):1073-85. doi: 10.1053/j.gastro.2006.07.018. Epub 2006 Jul 24. Gastroenterology. 2006. PMID: 17030178

7

Cytokine signalling by gp130 regulates gastric mucosal healing after ulceration and, indirectly, antral tumour progression.

Judd LM, Ulaganathan M, Howlett M, Giraud AS. Judd LM, et al. Among authors: giraud as. J Pathol. 2009 Mar;217(4):552-62. doi: 10.1002/path.2479. J Pathol. 2009. PMID: 19097069

8

The interleukin-6 family cytokine interleukin-11 regulates homeostatic epithelial cell turnover and promotes gastric tumor development.

Howlett M, Giraud AS, Lescesen H, Jackson CB, Kalantzis A, Van Driel IR, Robb L, Van der Hoek M, Ernst M, Minamoto T, Boussioutas A, Oshima H, Oshima M, Judd LM. Howlett M, et al. Among authors: giraud as. Gastroenterology. 2009 Mar;136(3):967-77. doi: 10.1053/j.gastro.2008.12.003. Epub 2008 Dec 3. Gastroenterology. 2009. PMID: 19121317

9

Helicobacter pylori CagA triggers expression of the bactericidal lectin REG3γ via gastric STAT3 activation.

Lee KS, Kalantzis A, Jackson CB, O'Connor L, Murata-Kamiya N, Hatakeyama M, Judd LM, Giraud AS, Menheniott TR. Lee KS, et al. Among authors: giraud as. PLoS One. 2012;7(2):e30786. doi: 10.1371/journal.pone.0030786. Epub 2012 Feb 1. PLoS One. 2012. PMID: 22312430 Free PMC article.

10

IL-1RT1 signaling antagonizes IL-11 induced STAT3 dependent cardiac and antral stomach tumor development through myeloid cell enrichment.

Buzzelli JN, Pavlic DI, Chalinor HV, O'Connor L, Menheniott TR, Giraud AS, Judd LM. Buzzelli JN, et al. Among authors: giraud as. Oncotarget. 2015 Jan 20;6(2):679-95. doi: 10.18632/oncotarget.2707. Oncotarget. 2015. PMID: 25528766 Free PMC article.

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