Wu D - Search Results

1

Enantioselective synthesis of a highly potent selective serotonin reuptake inhibitor. An application of imidazolidinone catalysis to the alkylation of indoles with an alpha,beta-disubstituted alpha,beta-unsaturated aldehyde.

King HD, Meng Z, Denhart D, Mattson R, Kimura R, Wu D, Gao Q, Macor JE. King HD, et al. Among authors: wu d. Org Lett. 2005 Aug 4;7(16):3437-40. doi: 10.1021/ol051000c. Org Lett. 2005. PMID: 16048311

2

Stereoselective synthesis of new conformationally restricted analogues of a potent CGRP receptor antagonist.

Zuev D, Michne JA, Huang H, Beno BR, Wu D, Gao Q, Torrente JR, Xu C, Conway CM, Macor JE, Dubowchik GM. Zuev D, et al. Among authors: wu d. Org Lett. 2005 Jun 9;7(12):2465-8. doi: 10.1021/ol0510062. Org Lett. 2005. PMID: 15932224

3

Synthesis of fluorinated 1-(3-morpholin-4-yl-phenyl)-ethylamines.

Wu YJ, He H, Sun LQ, Wu D, Gao Q, Li HY. Wu YJ, et al. Among authors: wu d. Bioorg Med Chem Lett. 2003 May 19;13(10):1725-8. doi: 10.1016/s0960-894x(03)00240-3. Bioorg Med Chem Lett. 2003. PMID: 12729651

4

Novel 3',6'-anhydro and N12,N13-bridged glycosylated fluoroindolo[2,3-a]carbazoles as topoisomerase I inhibitors. Fluorine as a leaving group from sp3 carbon.

Saulnier MG, Langley DR, Frennesson DB, Long BH, Huang S, Gao Q, Wu D, Fairchild CR, Ruediger E, Zimmermann K, St Laurent DR, Balasubramanian BN, Vyas DM. Saulnier MG, et al. Among authors: wu d. Org Lett. 2005 Mar 31;7(7):1271-4. doi: 10.1021/ol050013n. Org Lett. 2005. PMID: 15787484

5

Catalytic asymmetric syntheses of tyrosine surrogates.

Han X, Civiello RL, Fang H, Wu D, Gao Q, Chaturvedula PV, Macor JE, Dubowchik GM. Han X, et al. Among authors: wu d. J Org Chem. 2008 Nov 7;73(21):8502-10. doi: 10.1021/jo801577t. Epub 2008 Oct 15. J Org Chem. 2008. PMID: 18855485

6

Synthesis and hSERT activity of homotryptamine analogs. Part 6: [3+2] dipolar cycloaddition of 3-vinylindoles.

Marcin LR, Mattson RJ, Gao Q, Wu D, Molski TF, Mattson GK, Lodge NJ. Marcin LR, et al. Among authors: wu d. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1027-30. doi: 10.1016/j.bmcl.2009.12.043. Epub 2009 Dec 16. Bioorg Med Chem Lett. 2010. PMID: 20034793

7

Discovery of 6-chloro-2-trifluoromethyl-7-aryl-7H-imidazo[1,2-a]imidazol-3-ylmethylamines, a novel class of corticotropin-releasing factor receptor type 1 (CRF1R) antagonists.

Zuev D, Vrudhula VM, Michne JA, Dasgupta B, Pin SS, Huang XS, Wu D, Gao Q, Zhang J, Taber MT, Macor JE, Dubowchik GM. Zuev D, et al. Among authors: wu d. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3669-74. doi: 10.1016/j.bmcl.2010.04.094. Epub 2010 Apr 24. Bioorg Med Chem Lett. 2010. PMID: 20471832

8

Potential CRF1R PET imaging agents: N-fluoroalkyl-8-(6-methoxy-2-methylpyridin-3-yl)-2,7-dimethyl-N-alkylpyrazolo[1,5-a][1,3,5]triazin-4-amines.

Zuev D, Mattson RJ, Huang H, Mattson GK, Zueva L, Nielsen JM, Kozlowski ES, Huang XS, Wu D, Gao Q, Lodge NJ, Bronson JJ, Macor JE. Zuev D, et al. Among authors: wu d. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2484-8. doi: 10.1016/j.bmcl.2011.02.050. Epub 2011 Feb 17. Bioorg Med Chem Lett. 2011. PMID: 21411322

9

Discovery of a cyclopentylamine as an orally active dual NK1 receptor antagonist-serotonin reuptake transporter inhibitor.

Wu YJ, He H, Gao Q, Wu D, Bertekap R, Westphal RS, Lelas S, Newton A, Wallace T, Taber M, Davis C, Macor JE, Bronson J. Wu YJ, et al. Among authors: wu d. Bioorg Med Chem Lett. 2014 Mar 15;24(6):1611-4. doi: 10.1016/j.bmcl.2014.01.036. Epub 2014 Jan 27. Bioorg Med Chem Lett. 2014. PMID: 24507922

10

Identification of a potent and selective 5-HT(6) antagonist: one-step synthesis of (E)-3-(benzenesulfonyl)-2- (methylsulfanyl)pyrido[1,2-a]pyrimidin-4-ylidenamine from 2-(benzenesulfonyl)-3,3-bis(methylsulfanyl)acrylonitrile.

Wu YJ, He H, Hu S, Huang Y, Scola PM, Grant-Young K, Bertekap RL, Wu D, Gao Q, Li Y, Klakouski C, Westphal RS. Wu YJ, et al. Among authors: wu d. J Med Chem. 2003 Nov 6;46(23):4834-7. doi: 10.1021/jm034142q. J Med Chem. 2003. PMID: 14584934

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