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Serial passage through human glioma xenografts selects for a Deltagamma134.5 herpes simplex virus type 1 mutant that exhibits decreased neurotoxicity and prolongs survival of mice with experimental brain tumors.
Shah AC, Price KH, Parker JN, Samuel SL, Meleth S, Cassady KA, Gillespie GY, Whitley RJ, Markert JM. Shah AC, et al. Among authors: gillespie gy. J Virol. 2006 Aug;80(15):7308-15. doi: 10.1128/JVI.00725-06. J Virol. 2006. PMID: 16840311 Free PMC article.
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