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The AIDS resistance of naturally SIV-infected sooty mangabeys is independent of cellular immunity to the virus.
Dunham R, Pagliardini P, Gordon S, Sumpter B, Engram J, Moanna A, Paiardini M, Mandl JN, Lawson B, Garg S, McClure HM, Xu YX, Ibegbu C, Easley K, Katz N, Pandrea I, Apetrei C, Sodora DL, Staprans SI, Feinberg MB, Silvestri G. Dunham R, et al. Among authors: sodora dl. Blood. 2006 Jul 1;108(1):209-17. doi: 10.1182/blood-2005-12-4897. Epub 2006 Mar 7. Blood. 2006. PMID: 16522814 Free PMC article.
Virally induced CD4+ T cell depletion is not sufficient to induce AIDS in a natural host.
Milush JM, Reeves JD, Gordon SN, Zhou D, Muthukumar A, Kosub DA, Chacko E, Giavedoni LD, Ibegbu CC, Cole KS, Miamidian JL, Paiardini M, Barry AP, Staprans SI, Silvestri G, Sodora DL. Milush JM, et al. Among authors: sodora dl. J Immunol. 2007 Sep 1;179(5):3047-56. doi: 10.4049/jimmunol.179.5.3047. J Immunol. 2007. PMID: 17709519
Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4+ T cell loss is associated with double-negative T cells.
Milush JM, Mir KD, Sundaravaradan V, Gordon SN, Engram J, Cano CA, Reeves JD, Anton E, O'Neill E, Butler E, Hancock K, Cole KS, Brenchley JM, Else JG, Silvestri G, Sodora DL. Milush JM, et al. Among authors: sodora dl. J Clin Invest. 2011 Mar;121(3):1102-10. doi: 10.1172/JCI44876. Epub 2011 Feb 7. J Clin Invest. 2011. PMID: 21317533 Free PMC article.
Correlates of preserved CD4(+) T cell homeostasis during natural, nonpathogenic simian immunodeficiency virus infection of sooty mangabeys: implications for AIDS pathogenesis.
Sumpter B, Dunham R, Gordon S, Engram J, Hennessy M, Kinter A, Paiardini M, Cervasi B, Klatt N, McClure H, Milush JM, Staprans S, Sodora DL, Silvestri G. Sumpter B, et al. Among authors: sodora dl. J Immunol. 2007 Feb 1;178(3):1680-91. doi: 10.4049/jimmunol.178.3.1680. J Immunol. 2007. PMID: 17237418
97 results