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In vivo evidence of CHIP up-regulation attenuating tau aggregation.
Sahara N, Murayama M, Mizoroki T, Urushitani M, Imai Y, Takahashi R, Murata S, Tanaka K, Takashima A. Sahara N, et al. Among authors: murayama m. J Neurochem. 2005 Sep;94(5):1254-63. doi: 10.1111/j.1471-4159.2005.03272.x. J Neurochem. 2005. PMID: 16111477 Free article.
U-box protein carboxyl terminus of Hsc70-interacting protein (CHIP) mediates poly-ubiquitylation preferentially on four-repeat Tau and is involved in neurodegeneration of tauopathy.
Hatakeyama S, Matsumoto M, Kamura T, Murayama M, Chui DH, Planel E, Takahashi R, Nakayama KI, Takashima A. Hatakeyama S, et al. Among authors: murayama m. J Neurochem. 2004 Oct;91(2):299-307. doi: 10.1111/j.1471-4159.2004.02713.x. J Neurochem. 2004. PMID: 15447663 Free article.
Granular tau oligomers as intermediates of tau filaments.
Maeda S, Sahara N, Saito Y, Murayama M, Yoshiike Y, Kim H, Miyasaka T, Murayama S, Ikai A, Takashima A. Maeda S, et al. Among authors: murayama m, murayama s. Biochemistry. 2007 Mar 27;46(12):3856-61. doi: 10.1021/bi061359o. Epub 2007 Mar 6. Biochemistry. 2007. PMID: 17338548
Aluminum induces tau aggregation in vitro but not in vivo.
Mizoroki T, Meshitsuka S, Maeda S, Murayama M, Sahara N, Takashima A. Mizoroki T, et al. Among authors: murayama m. J Alzheimers Dis. 2007 Jul;11(4):419-27. doi: 10.3233/jad-2007-11401. J Alzheimers Dis. 2007. PMID: 17656819
743 results