Broaddus VC - Search Results

1

A novel in vitro model of human mesothelioma for studying tumor biology and apoptotic resistance.

Kim KU, Wilson SM, Abayasiriwardana KS, Collins R, Fjellbirkeland L, Xu Z, Jablons DM, Nishimura SL, Broaddus VC. Kim KU, et al. Among authors: broaddus vc. Am J Respir Cell Mol Biol. 2005 Dec;33(6):541-8. doi: 10.1165/rcmb.2004-0355OC. Epub 2005 Aug 25. Am J Respir Cell Mol Biol. 2005. PMID: 16123394 Free PMC article.

2

Sensitization of mesothelioma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by heat stress via the inhibition of the 3-phosphoinositide-dependent kinase 1/Akt pathway.

Pespeni MH, Hodnett M, Abayasiriwardana KS, Roux J, Howard M, Broaddus VC, Pittet JF. Pespeni MH, et al. Among authors: broaddus vc. Cancer Res. 2007 Mar 15;67(6):2865-71. doi: 10.1158/0008-5472.CAN-06-3871. Cancer Res. 2007. PMID: 17363610

3

Malignant mesothelioma cells are rapidly sensitized to TRAIL-induced apoptosis by low-dose anisomycin via Bim.

Abayasiriwardana KS, Barbone D, Kim KU, Vivo C, Lee KK, Dansen TB, Hunt AE, Evan GI, Broaddus VC. Abayasiriwardana KS, et al. Among authors: broaddus vc. Mol Cancer Ther. 2007 Oct;6(10):2766-76. doi: 10.1158/1535-7163.MCT-07-0278. Mol Cancer Ther. 2007. PMID: 17938269

4

mTOR mediates survival signals in malignant mesothelioma grown as tumor fragment spheroids.

Wilson SM, Barbone D, Yang TM, Jablons DM, Bueno R, Sugarbaker DJ, Nishimura SL, Gordon GJ, Broaddus VC. Wilson SM, et al. Among authors: broaddus vc. Am J Respir Cell Mol Biol. 2008 Nov;39(5):576-83. doi: 10.1165/rcmb.2007-0460OC. Epub 2008 May 29. Am J Respir Cell Mol Biol. 2008. PMID: 18511708 Free PMC article.

5

Bid mediates apoptotic synergy between tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and DNA damage.

Broaddus VC, Dansen TB, Abayasiriwardana KS, Wilson SM, Finch AJ, Swigart LB, Hunt AE, Evan GI. Broaddus VC, et al. J Biol Chem. 2005 Apr 1;280(13):12486-93. doi: 10.1074/jbc.M408190200. Epub 2004 Dec 22. J Biol Chem. 2005. PMID: 15615731 Free article.

6

The integrin alpha(v)beta8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-beta1.

Mu D, Cambier S, Fjellbirkeland L, Baron JL, Munger JS, Kawakatsu H, Sheppard D, Broaddus VC, Nishimura SL. Mu D, et al. Among authors: broaddus vc. J Cell Biol. 2002 Apr 29;157(3):493-507. doi: 10.1083/jcb.200109100. Epub 2002 Apr 22. J Cell Biol. 2002. PMID: 11970960 Free PMC article.

7

Integrin alphavbeta8-mediated activation of transforming growth factor-beta inhibits human airway epithelial proliferation in intact bronchial tissue.

Fjellbirkeland L, Cambier S, Broaddus VC, Hill A, Brunetta P, Dolganov G, Jablons D, Nishimura SL. Fjellbirkeland L, et al. Among authors: broaddus vc. Am J Pathol. 2003 Aug;163(2):533-42. doi: 10.1016/s0002-9440(10)63681-4. Am J Pathol. 2003. PMID: 12875973 Free PMC article.

8

Targeted drug delivery to mesothelioma cells using functionally selected internalizing human single-chain antibodies.

An F, Drummond DC, Wilson S, Kirpotin DB, Nishimura SL, Broaddus VC, Liu B. An F, et al. Among authors: broaddus vc. Mol Cancer Ther. 2008 Mar;7(3):569-78. doi: 10.1158/1535-7163.MCT-07-2132. Epub 2008 Mar 4. Mol Cancer Ther. 2008. PMID: 18319332 Free PMC article.

9

Tumor necrosis factor-related apoptosis-inducing ligand and chemotherapy cooperate to induce apoptosis in mesothelioma cell lines.

Liu W, Bodle E, Chen JY, Gao M, Rosen GD, Broaddus VC. Liu W, et al. Among authors: broaddus vc. Am J Respir Cell Mol Biol. 2001 Jul;25(1):111-8. doi: 10.1165/ajrcmb.25.1.4472. Am J Respir Cell Mol Biol. 2001. PMID: 11472983

10

The Bcl-2 repertoire of mesothelioma spheroids underlies acquired apoptotic multicellular resistance.

Barbone D, Ryan JA, Kolhatkar N, Chacko AD, Jablons DM, Sugarbaker DJ, Bueno R, Letai AG, Coussens LM, Fennell DA, Broaddus VC. Barbone D, et al. Among authors: broaddus vc. Cell Death Dis. 2011 Jun 23;2(6):e174. doi: 10.1038/cddis.2011.58. Cell Death Dis. 2011. PMID: 21697949 Free PMC article.

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