Circulating levels of IGF-1 directly regulate bone growth and density.
Yakar S, Rosen CJ, Beamer WG, Ackert-Bicknell CL, Wu Y, Liu JL, Ooi GT, Setser J, Frystyk J, Boisclair YR, LeRoith D.
Yakar S, et al.
J Clin Invest. 2002 Sep;110(6):771-81. doi: 10.1172/JCI15463.
J Clin Invest. 2002.
PMID: 12235108
Free PMC article.