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Cardiac stem cells possess growth factor-receptor systems that after activation regenerate the infarcted myocardium, improving ventricular function and long-term survival.
Urbanek K, Rota M, Cascapera S, Bearzi C, Nascimbene A, De Angelis A, Hosoda T, Chimenti S, Baker M, Limana F, Nurzynska D, Torella D, Rotatori F, Rastaldo R, Musso E, Quaini F, Leri A, Kajstura J, Anversa P. Urbanek K, et al. Among authors: torella d. Circ Res. 2005 Sep 30;97(7):663-73. doi: 10.1161/01.RES.0000183733.53101.11. Epub 2005 Sep 1. Circ Res. 2005. PMID: 16141414
Intense myocyte formation from cardiac stem cells in human cardiac hypertrophy.
Urbanek K, Quaini F, Tasca G, Torella D, Castaldo C, Nadal-Ginard B, Leri A, Kajstura J, Quaini E, Anversa P. Urbanek K, et al. Among authors: torella d. Proc Natl Acad Sci U S A. 2003 Sep 2;100(18):10440-5. doi: 10.1073/pnas.1832855100. Epub 2003 Aug 19. Proc Natl Acad Sci U S A. 2003. PMID: 12928492 Free PMC article.
Adult cardiac stem cells are multipotent and support myocardial regeneration.
Beltrami AP, Barlucchi L, Torella D, Baker M, Limana F, Chimenti S, Kasahara H, Rota M, Musso E, Urbanek K, Leri A, Kajstura J, Nadal-Ginard B, Anversa P. Beltrami AP, et al. Among authors: torella d. Cell. 2003 Sep 19;114(6):763-76. doi: 10.1016/s0092-8674(03)00687-1. Cell. 2003. PMID: 14505575 Free article.
Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes.
Shiraishi I, Melendez J, Ahn Y, Skavdahl M, Murphy E, Welch S, Schaefer E, Walsh K, Rosenzweig A, Torella D, Nurzynska D, Kajstura J, Leri A, Anversa P, Sussman MA. Shiraishi I, et al. Among authors: torella d. Circ Res. 2004 Apr 16;94(7):884-91. doi: 10.1161/01.RES.0000124394.01180.BE. Epub 2004 Feb 26. Circ Res. 2004. PMID: 14988230
Bone marrow cells differentiate in cardiac cell lineages after infarction independently of cell fusion.
Kajstura J, Rota M, Whang B, Cascapera S, Hosoda T, Bearzi C, Nurzynska D, Kasahara H, Zias E, Bonafé M, Nadal-Ginard B, Torella D, Nascimbene A, Quaini F, Urbanek K, Leri A, Anversa P. Kajstura J, et al. Among authors: torella d. Circ Res. 2005 Jan 7;96(1):127-37. doi: 10.1161/01.RES.0000151843.79801.60. Epub 2004 Nov 29. Circ Res. 2005. PMID: 15569828
Cardiac stem cells delivered intravascularly traverse the vessel barrier, regenerate infarcted myocardium, and improve cardiac function.
Dawn B, Stein AB, Urbanek K, Rota M, Whang B, Rastaldo R, Torella D, Tang XL, Rezazadeh A, Kajstura J, Leri A, Hunt G, Varma J, Prabhu SD, Anversa P, Bolli R. Dawn B, et al. Among authors: torella d. Proc Natl Acad Sci U S A. 2005 Mar 8;102(10):3766-71. doi: 10.1073/pnas.0405957102. Epub 2005 Feb 25. Proc Natl Acad Sci U S A. 2005. PMID: 15734798 Free PMC article.
Myocardial regeneration by activation of multipotent cardiac stem cells in ischemic heart failure.
Urbanek K, Torella D, Sheikh F, De Angelis A, Nurzynska D, Silvestri F, Beltrami CA, Bussani R, Beltrami AP, Quaini F, Bolli R, Leri A, Kajstura J, Anversa P. Urbanek K, et al. Among authors: torella d. Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8692-7. doi: 10.1073/pnas.0500169102. Epub 2005 Jun 2. Proc Natl Acad Sci U S A. 2005. PMID: 15932947 Free PMC article.
Stem cells in the dog heart are self-renewing, clonogenic, and multipotent and regenerate infarcted myocardium, improving cardiac function.
Linke A, Müller P, Nurzynska D, Casarsa C, Torella D, Nascimbene A, Castaldo C, Cascapera S, Böhm M, Quaini F, Urbanek K, Leri A, Hintze TH, Kajstura J, Anversa P. Linke A, et al. Among authors: torella d. Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):8966-71. doi: 10.1073/pnas.0502678102. Epub 2005 Jun 10. Proc Natl Acad Sci U S A. 2005. PMID: 15951423 Free PMC article.
185 results