Tortorella P - Search Results

1

AMBER force field implementation of the boronate function to simulate the inhibition of beta-lactamases by alkyl and aryl boronic acids.

Tafi A, Agamennone M, Tortorella P, Alcaro S, Gallina C, Botta M. Tafi A, et al. Among authors: tortorella p. Eur J Med Chem. 2005 Nov;40(11):1134-42. doi: 10.1016/j.ejmech.2005.06.011. Epub 2005 Sep 8. Eur J Med Chem. 2005. PMID: 16153747

2

Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na(+) channels.

Franchini C, Carocci A, Catalano A, Cavalluzzi MM, Corbo F, Lentini G, Scilimati A, Tortorella P, Camerino DC, De Luca A. Franchini C, et al. Among authors: tortorella p. J Med Chem. 2003 Nov 20;46(24):5238-48. doi: 10.1021/jm030865y. J Med Chem. 2003. PMID: 14613326

3

Synthesis and evaluation of new tripeptide phosphonate inhibitors of MMP-8 and MMP-2.

Agamennone M, Campestre C, Preziuso S, Consalvi V, Crucianelli M, Mazza F, Politi V, Ragno R, Tortorella P, Gallina C. Agamennone M, et al. Among authors: tortorella p. Eur J Med Chem. 2005 Mar;40(3):271-9. doi: 10.1016/j.ejmech.2004.10.013. Epub 2005 Jan 19. Eur J Med Chem. 2005. PMID: 15725496

4

N-Hydroxyurea as zinc binding group in matrix metalloproteinase inhibition: mode of binding in a complex with MMP-8.

Campestre C, Agamennone M, Tortorella P, Preziuso S, Biasone A, Gavuzzo E, Pochetti G, Mazza F, Hiller O, Tschesche H, Consalvi V, Gallina C. Campestre C, et al. Among authors: tortorella p. Bioorg Med Chem Lett. 2006 Jan 1;16(1):20-4. doi: 10.1016/j.bmcl.2005.09.057. Epub 2005 Oct 18. Bioorg Med Chem Lett. 2006. PMID: 16242329

5

Structural insight into the stereoselective inhibition of MMP-8 by enantiomeric sulfonamide phosphonates.

Pochetti G, Gavuzzo E, Campestre C, Agamennone M, Tortorella P, Consalvi V, Gallina C, Hiller O, Tschesche H, Tucker PA, Mazza F. Pochetti G, et al. Among authors: tortorella p. J Med Chem. 2006 Feb 9;49(3):923-31. doi: 10.1021/jm050787+. J Med Chem. 2006. PMID: 16451058

6

alpha-Biphenylsulfonylamino 2-methylpropyl phosphonates: enantioselective synthesis and selective inhibition of MMPs.

Biasone A, Tortorella P, Campestre C, Agamennone M, Preziuso S, Chiappini M, Nuti E, Carelli P, Rossello A, Mazza F, Gallina C. Biasone A, et al. Among authors: tortorella p. Bioorg Med Chem. 2007 Jan 15;15(2):791-9. doi: 10.1016/j.bmc.2006.10.047. Epub 2006 Oct 25. Bioorg Med Chem. 2007. PMID: 17088065

7

Peptidyl 3-substituted 1-hydroxyureas as isosteric analogues of succinylhydroxamate MMP inhibitors.

Campestre C, Tortorella P, Agamennone M, Preziuso S, Biasone A, Nuti E, Rossello A, Gallina C. Campestre C, et al. Among authors: tortorella p. Eur J Med Chem. 2008 May;43(5):1008-14. doi: 10.1016/j.ejmech.2007.07.002. Epub 2007 Jul 15. Eur J Med Chem. 2008. PMID: 17719700

8

Synthesis, biological evaluation, and molecular modeling investigation of chiral 2-(4-chloro-phenoxy)-3-phenyl-propanoic acid derivatives with PPARalpha and PPARgamma agonist activity.

Fracchiolla G, Lavecchia A, Laghezza A, Piemontese L, Trisolini R, Carbonara G, Tortorella P, Novellino E, Loiodice F. Fracchiolla G, et al. Among authors: tortorella p. Bioorg Med Chem. 2008 Nov 1;16(21):9498-510. doi: 10.1016/j.bmc.2008.09.045. Epub 2008 Sep 19. Bioorg Med Chem. 2008. PMID: 18835719

9

Synthesis, SAR, and biological evaluation of alpha-sulfonylphosphonic acids as selective matrix metalloproteinase inhibitors.

Rubino MT, Agamennone M, Campestre C, Fracchiolla G, Laghezza A, Loiodice F, Nuti E, Rossello A, Tortorella P. Rubino MT, et al. Among authors: tortorella p. ChemMedChem. 2009 Mar;4(3):352-62. doi: 10.1002/cmdc.200800324. ChemMedChem. 2009. PMID: 19204958

10

New 2-aryloxy-3-phenyl-propanoic acids as peroxisome proliferator-activated receptors alpha/gamma dual agonists with improved potency and reduced adverse effects on skeletal muscle function.

Fracchiolla G, Laghezza A, Piemontese L, Tortorella P, Mazza F, Montanari R, Pochetti G, Lavecchia A, Novellino E, Pierno S, Conte Camerino D, Loiodice F. Fracchiolla G, et al. Among authors: tortorella p. J Med Chem. 2009 Oct 22;52(20):6382-93. doi: 10.1021/jm900941b. J Med Chem. 2009. PMID: 19775169

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