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Adult human kidney organoids originate from CD24+ cells and represent an advanced model for adult polycystic kidney disease.
Xu Y, Kuppe C, Perales-Patón J, Hayat S, Kranz J, Abdallah AT, Nagai J, Li Z, Peisker F, Saritas T, Halder M, Menzel S, Hoeft K, Kenter A, Kim H, van Roeyen CRC, Lehrke M, Moellmann J, Speer T, Buhl EM, Hoogenboezem R, Boor P, Jansen J, Knopp C, Kurth I, Smeets B, Bindels E, Reinders MEJ, Baan C, Gribnau J, Hoorn EJ, Steffens J, Huber TB, Costa I, Floege J, Schneider RK, Saez-Rodriguez J, Freedman BS, Kramann R. Xu Y, et al. Among authors: smeets b. Nat Genet. 2022 Nov;54(11):1690-1701. doi: 10.1038/s41588-022-01202-z. Epub 2022 Oct 27. Nat Genet. 2022. PMID: 36303074 Free PMC article.
Tubuloid culture enables long-term expansion of functional human kidney tubule epithelium from iPSC-derived organoids.
Yousef Yengej FA, Jansen J, Ammerlaan CME, Dilmen E, Pou Casellas C, Masereeuw R, Hoenderop JG, Smeets B, Rookmaaker MB, Verhaar MC, Clevers H. Yousef Yengej FA, et al. Among authors: smeets b. Proc Natl Acad Sci U S A. 2023 Feb 7;120(6):e2216836120. doi: 10.1073/pnas.2216836120. Epub 2023 Feb 1. Proc Natl Acad Sci U S A. 2023. PMID: 36724260 Free PMC article.
Renal progenitor cells contribute to hyperplastic lesions of podocytopathies and crescentic glomerulonephritis.
Smeets B, Angelotti ML, Rizzo P, Dijkman H, Lazzeri E, Mooren F, Ballerini L, Parente E, Sagrinati C, Mazzinghi B, Ronconi E, Becherucci F, Benigni A, Steenbergen E, Lasagni L, Remuzzi G, Wetzels J, Romagnani P. Smeets B, et al. J Am Soc Nephrol. 2009 Dec;20(12):2593-603. doi: 10.1681/ASN.2009020132. Epub 2009 Oct 29. J Am Soc Nephrol. 2009. PMID: 19875807 Free PMC article.
139 results