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The phosphatidylinositol-3-kinase inhibitor PX-866 overcomes resistance to the epidermal growth factor receptor inhibitor gefitinib in A-549 human non-small cell lung cancer xenografts.
Ihle NT, Paine-Murrieta G, Berggren MI, Baker A, Tate WR, Wipf P, Abraham RT, Kirkpatrick DL, Powis G. Ihle NT, et al. Among authors: powis g. Mol Cancer Ther. 2005 Sep;4(9):1349-57. doi: 10.1158/1535-7163.MCT-05-0149. Mol Cancer Ther. 2005. PMID: 16170026 Free PMC article.
Discovery of a novel class of AKT pleckstrin homology domain inhibitors.
Mahadevan D, Powis G, Mash EA, George B, Gokhale VM, Zhang S, Shakalya K, Du-Cuny L, Berggren M, Ali MA, Jana U, Ihle N, Moses S, Franklin C, Narayan S, Shirahatti N, Meuillet EJ. Mahadevan D, et al. Among authors: powis g. Mol Cancer Ther. 2008 Sep;7(9):2621-32. doi: 10.1158/1535-7163.MCT-07-2276. Mol Cancer Ther. 2008. PMID: 18790745 Free PMC article.
363 results