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The K121Q polymorphism of the ENPP1/PC-1 gene is associated with insulin resistance/atherogenic phenotypes, including earlier onset of type 2 diabetes and myocardial infarction.
Bacci S, Ludovico O, Prudente S, Zhang YY, Di Paola R, Mangiacotti D, Rauseo A, Nolan D, Duffy J, Fini G, Salvemini L, Amico C, Vigna C, Pellegrini F, Menzaghi C, Doria A, Trischitta V. Bacci S, et al. Among authors: doria a. Diabetes. 2005 Oct;54(10):3021-5. doi: 10.2337/diabetes.54.10.3021. Diabetes. 2005. PMID: 16186408
A common haplotype at the CD36 locus is associated with high free fatty acid levels and increased cardiovascular risk in Caucasians.
Ma X, Bacci S, Mlynarski W, Gottardo L, Soccio T, Menzaghi C, Iori E, Lager RA, Shroff AR, Gervino EV, Nesto RW, Johnstone MT, Abumrad NA, Avogaro A, Trischitta V, Doria A. Ma X, et al. Among authors: doria a. Hum Mol Genet. 2004 Oct 1;13(19):2197-205. doi: 10.1093/hmg/ddh233. Epub 2004 Jul 28. Hum Mol Genet. 2004. PMID: 15282206
1,295 results