Middlemiss D - Search Results

1

Indole-3-acetic acid antagonists of the prostaglandin D2 receptor CRTH2.

Armer RE, Ashton MR, Boyd EA, Brennan CJ, Brookfield FA, Gazi L, Gyles SL, Hay PA, Hunter MG, Middlemiss D, Whittaker M, Xue L, Pettipher R. Armer RE, et al. Among authors: middlemiss d. J Med Chem. 2005 Oct 6;48(20):6174-7. doi: 10.1021/jm050519b. J Med Chem. 2005. PMID: 16190744

2

Bromobenzofuran-based non-peptide antagonists of angiotensin II: GR138950, a potent antihypertensive agent with high oral bioavailability.

Judd DB, Dowle MD, Middlemiss D, Scopes DI, Ross BC, Jack TI, Pass M, Tranquillini E, Hobson JE, Panchal TA, et al. Judd DB, et al. Among authors: middlemiss d. J Med Chem. 1994 Sep 16;37(19):3108-20. doi: 10.1021/jm00045a016. J Med Chem. 1994. PMID: 7932534

3

Discovery of an orally bioavailable NK1 receptor antagonist, (2S,3S)-(2-methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl)amine (GR203040), with potent antiemetic activity.

Ward P, Armour DR, Bays DE, Evans B, Giblin GM, Heron N, Hubbard T, Liang K, Middlemiss D, Mordaunt J, et al. Ward P, et al. Among authors: middlemiss d. J Med Chem. 1995 Dec 22;38(26):4985-92. doi: 10.1021/jm00026a005. J Med Chem. 1995. PMID: 8544174

4

Absolute configuration of the optical isomers of salbutamol.

Hartley D, Middlemiss D. Hartley D, et al. Among authors: middlemiss d. J Med Chem. 1971 Sep;14(9):995-6. doi: 10.1021/jm00291a036. J Med Chem. 1971. PMID: 4400869 No abstract available.

5

Pharmacological profile of GR117289 in vitro: a novel, potent and specific non-peptide angiotensin AT1 receptor antagonist.

Robertson MJ, Barnes JC, Drew GM, Clark KL, Marshall FH, Michel A, Middlemiss D, Ross BC, Scopes D, Dowle MD. Robertson MJ, et al. Among authors: middlemiss d. Br J Pharmacol. 1992 Dec;107(4):1173-80. doi: 10.1111/j.1476-5381.1992.tb13425.x. Br J Pharmacol. 1992. PMID: 1467838 Free PMC article.

6

Pharmacological effects of GR138950, a novel angiotensin AT1 receptor antagonist.

Hilditch A, Hunt AA, Travers A, Polley J, Drew GM, Middlemiss D, Judd DB, Ross BC, Robertson MJ. Hilditch A, et al. Among authors: middlemiss d. J Pharmacol Exp Ther. 1995 Feb;272(2):750-7. J Pharmacol Exp Ther. 1995. PMID: 7853190

7

Cardiovascular effects of GR117289, a novel angiotensin AT1 receptor antagonist.

Hilditch A, Hunt AA, Gardner CJ, Twissell DJ, Polley J, Travers A, Drew GM, Middlemiss D, Ross BC, Robertson MJ. Hilditch A, et al. Among authors: middlemiss d. Br J Pharmacol. 1994 Jan;111(1):137-44. doi: 10.1111/j.1476-5381.1994.tb14035.x. Br J Pharmacol. 1994. PMID: 8012689 Free PMC article.

8

Synthesis of exo-3-phenylbicyclo[3.2.1]oct-3-en-2-amine and related compounds as potential analgesics.

Harris A, Middlemiss D, Mills K, Gower AJ, Tyers MB. Harris A, et al. Among authors: middlemiss d. J Med Chem. 1983 Jan;26(1):55-60. doi: 10.1021/jm00355a012. J Med Chem. 1983. PMID: 6681842

9

Comparative pharmacology of recombinant rat AT1A, AT1B and human AT1 receptors expressed by transfected COS-M6 cells.

Balmforth AJ, Bryson SE, Aylett AJ, Warburton P, Ball SG, Pun KT, Middlemiss D, Drew GM. Balmforth AJ, et al. Among authors: middlemiss d. Br J Pharmacol. 1994 May;112(1):277-81. doi: 10.1111/j.1476-5381.1994.tb13064.x. Br J Pharmacol. 1994. PMID: 8032651 Free PMC article.

10

Fragment-based and structure-guided discovery of perforin inhibitors.

Jose J, Law RHP, Leung EWW, Wai DCC, Akhlaghi H, Chandrashekaran IR, Caradoc-Davies TT, Voskoboinik I, Feutrill J, Middlemiss D, Jeevarajah D, Bashtannyk-Puhalovich T, Giddens AC, Lee TW, Jamieson SMF, Trapani JA, Whisstock JC, Spicer JA, Norton RS. Jose J, et al. Among authors: middlemiss d. Eur J Med Chem. 2023 Dec 5;261:115786. doi: 10.1016/j.ejmech.2023.115786. Epub 2023 Sep 1. Eur J Med Chem. 2023. PMID: 37716187 Free article.

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