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Page 1
Indole-3-acetic acid antagonists of the prostaglandin D2 receptor CRTH2.
Armer RE, Ashton MR, Boyd EA, Brennan CJ, Brookfield FA, Gazi L, Gyles SL, Hay PA, Hunter MG, Middlemiss D, Whittaker M, Xue L, Pettipher R. Armer RE, et al. Among authors: whittaker m. J Med Chem. 2005 Oct 6;48(20):6174-7. doi: 10.1021/jm050519b. J Med Chem. 2005. PMID: 16190744
The selection and design of GPCR ligands: from concept to the clinic.
Ashton M, Charlton MH, Schwarz MK, Thomas RJ, Whittaker M. Ashton M, et al. Among authors: whittaker m. Comb Chem High Throughput Screen. 2004 Aug;7(5):441-52. doi: 10.2174/1386207043328607. Comb Chem High Throughput Screen. 2004. PMID: 15320711 Review.
Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ.
Czaplewski LG, Collins I, Boyd EA, Brown D, East SP, Gardiner M, Fletcher R, Haydon DJ, Henstock V, Ingram P, Jones C, Noula C, Kennison L, Rockley C, Rose V, Thomaides-Brears HB, Ure R, Whittaker M, Stokes NR. Czaplewski LG, et al. Among authors: whittaker m. Bioorg Med Chem Lett. 2009 Jan 15;19(2):524-7. doi: 10.1016/j.bmcl.2008.11.021. Epub 2008 Nov 13. Bioorg Med Chem Lett. 2009. PMID: 19064318
Novel 6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene analogues as potent and selective 5-HT(2C) agonists for the treatment of metabolic disorders.
Tye H, Mueller SG, Prestle J, Scheuerer S, Schindler M, Nosse B, Prevost N, Brown CJ, Heifetz A, Moeller C, Pedret-Dunn A, Whittaker M. Tye H, et al. Among authors: whittaker m. Bioorg Med Chem Lett. 2011 Jan 1;21(1):34-7. doi: 10.1016/j.bmcl.2010.11.089. Epub 2010 Nov 24. Bioorg Med Chem Lett. 2011. PMID: 21146986
An orally bioavailable positive allosteric modulator of the mGlu4 receptor with efficacy in an animal model of motor dysfunction.
East SP, Bamford S, Dietz MG, Eickmeier C, Flegg A, Ferger B, Gemkow MJ, Heilker R, Hengerer B, Kotey A, Loke P, Schänzle G, Schubert HD, Scott J, Whittaker M, Williams M, Zawadzki P, Gerlach K. East SP, et al. Among authors: whittaker m. Bioorg Med Chem Lett. 2010 Aug 15;20(16):4901-5. doi: 10.1016/j.bmcl.2010.06.078. Epub 2010 Jun 25. Bioorg Med Chem Lett. 2010. PMID: 20638279
Asymmetric synthesis of BB-3497--a potent peptide deformylase inhibitor.
Pratt LM, Beckett RP, Davies SJ, Launchbury SB, Miller A, Spavold ZM, Todd RS, Whittaker M. Pratt LM, et al. Among authors: whittaker m. Bioorg Med Chem Lett. 2001 Oct 8;11(19):2585-8. doi: 10.1016/s0960-894x(01)00509-1. Bioorg Med Chem Lett. 2001. PMID: 11551755
Antibiotic activity and characterization of BB-3497, a novel peptide deformylase inhibitor.
Clements JM, Beckett RP, Brown A, Catlin G, Lobell M, Palan S, Thomas W, Whittaker M, Wood S, Salama S, Baker PJ, Rodgers HF, Barynin V, Rice DW, Hunter MG. Clements JM, et al. Among authors: whittaker m. Antimicrob Agents Chemother. 2001 Feb;45(2):563-70. doi: 10.1128/AAC.45.2.563-570.2001. Antimicrob Agents Chemother. 2001. PMID: 11158755 Free PMC article.
586 results