Bartolini A - Search Results

1

Design, synthesis, and preliminary pharmacological evaluation of a set of small molecules that directly activate gi proteins.

Manetti D, Di Cesare Mannelli L, Dei S, Galeotti N, Ghelardini C, Romanelli MN, Scapecchi S, Teodori E, Pacini A, Bartolini A, Gualtieri F. Manetti D, et al. Among authors: bartolini a. J Med Chem. 2005 Oct 6;48(20):6491-503. doi: 10.1021/jm050498l. J Med Chem. 2005. PMID: 16190775

2

[(3-Chlorophenyl)piperazinylpropyl]pyridazinones and analogues as potent antinociceptive agents.

Giovannoni MP, Vergelli C, Ghelardini C, Galeotti N, Bartolini A, Dal Piaz V. Giovannoni MP, et al. Among authors: bartolini a. J Med Chem. 2003 Mar 13;46(6):1055-9. doi: 10.1021/jm021057u. J Med Chem. 2003. PMID: 12620082

3

4-Aminopiperidine derivatives as a new class of potent cognition enhancing drugs.

Manetti D, Martini E, Ghelardini C, Dei S, Galeotti N, Guandalini L, Romanelli MN, Scapecchi S, Teodori E, Bartolini A, Gualtieri F. Manetti D, et al. Among authors: bartolini a. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2303-6. doi: 10.1016/s0960-894x(03)00437-2. Bioorg Med Chem Lett. 2003. PMID: 12824022

4

Hybridized and isosteric analogues of N1-acetyl-N4-dimethyl-piperazinium iodide (ADMP) and N1-phenyl-N4-dimethyl-piperazinium iodide (DMPP) with central nicotinic action.

Manetti D, Bartolini A, Borea PA, Bellucci C, Dei S, Ghelardini C, Gualtieri F, Romanelli MN, Scapecchi S, Teodori E, Varani K. Manetti D, et al. Among authors: bartolini a. Bioorg Med Chem. 1999 Mar;7(3):457-65. doi: 10.1016/s0968-0896(98)00259-4. Bioorg Med Chem. 1999. PMID: 10220032

5

Design, synthesis, and preliminary pharmacological evaluation of 1, 4-diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic agents.

Manetti D, Ghelardini C, Bartolini A, Bellucci C, Dei S, Galeotti N, Gualtieri F, Romanelli MN, Scapecchi S, Teodori E. Manetti D, et al. Among authors: bartolini a. J Med Chem. 2000 May 18;43(10):1969-74. doi: 10.1021/jm991170t. J Med Chem. 2000. PMID: 10821709

6

Molecular simplification of 1,4-diazabicyclo[4.3.0]nonan-9-ones gives piperazine derivatives that maintain high nootropic activity.

Manetti D, Ghelardini C, Bartolini A, Dei S, Galeotti N, Gualtieri F, Romanelli MN, Teodori E. Manetti D, et al. Among authors: bartolini a. J Med Chem. 2000 Nov 16;43(23):4499-507. doi: 10.1021/jm000972h. J Med Chem. 2000. PMID: 11087574

7

Structure-affinity relationships of a unique nicotinic ligand: N(1)-dimethyl-N(4)-phenylpiperazinium iodide (DMPP).

Romanelli MN, Manetti D, Scapecchi S, Borea PA, Dei S, Bartolini A, Ghelardini C, Gualtieri F, Guandalini L, Varani K. Romanelli MN, et al. Among authors: bartolini a. J Med Chem. 2001 Nov 8;44(23):3946-55. doi: 10.1021/jm010901y. J Med Chem. 2001. PMID: 11689081

8

Gi/o proteins: expression for direct activation enquiry.

Di Cesare Mannelli L, Pacini A, Toscano A, Fortini M, Berti D, Ghelardini C, Galeotti N, Baglioni P, Bartolini A. Di Cesare Mannelli L, et al. Among authors: bartolini a. Protein Expr Purif. 2006 May;47(1):303-10. doi: 10.1016/j.pep.2005.11.005. Epub 2005 Dec 5. Protein Expr Purif. 2006. PMID: 16364655

9

A recombinant transductor-effector system: in vitro study of G inhibitory protein (G-alpha-i1) direct activators.

Di Cesare Mannelli L, Pacini A, Toscano A, Ghelardini C, Manetti D, Gualtieri F, Patel TB, Bartolini A. Di Cesare Mannelli L, et al. Among authors: bartolini a. Arch Biochem Biophys. 2006 Sep 15;453(2):151-60. doi: 10.1016/j.abb.2006.07.006. Epub 2006 Aug 2. Arch Biochem Biophys. 2006. PMID: 16919234

10

Receptor-independent modulation of reconstituted Galpha(i) protein mediated by liposomes.

Luciani P, Berti D, Fortini M, Baglioni P, Ghelardini C, Pacini A, Manetti D, Gualtieri F, Bartolini A, Di Cesare Mannelli L. Luciani P, et al. Among authors: bartolini a. Mol Biosyst. 2009 Apr;5(4):356-67. doi: 10.1039/b815042g. Epub 2009 Jan 29. Mol Biosyst. 2009. PMID: 19396372

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