Birch HL - Search Results

1

Novel 7-methoxy-6-oxazol-5-yl-2,3-dihydro-1H-quinazolin-4-ones as IMPDH inhibitors.

Birch HL, Buckley GM, Davies N, Dyke HJ, Frost EJ, Gilbert PJ, Hannah DR, Haughan AF, Madigan MJ, Morgan T, Pitt WR, Ratcliffe AJ, Ray NC, Richard MD, Sharpe A, Taylor AJ, Whitworth JM, Williams SC. Birch HL, et al. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5335-9. doi: 10.1016/j.bmcl.2005.06.108. Epub 2005 Oct 3. Bioorg Med Chem Lett. 2005. PMID: 16202581

2

Development of CXCR3 antagonists. Part 2: Identification of 2-amino(4-piperidinyl)azoles as potent CXCR3 antagonists.

Watson RJ, Allen DR, Birch HL, Chapman GA, Hannah DR, Knight RL, Meissner JW, Owen DA, Thomas EJ. Watson RJ, et al. Among authors: birch hl. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6806-10. doi: 10.1016/j.bmcl.2007.10.029. Epub 2007 Oct 17. Bioorg Med Chem Lett. 2007. PMID: 17964154

3

Development of CXCR3 antagonists. Part 4: discovery of 2-amino-(4-tropinyl)quinolines.

Knight RL, Allen DR, Birch HL, Chapman GA, Galvin FC, Jopling LA, Lock CJ, Meissner JW, Owen DA, Raphy G, Watson RJ, Williams SC. Knight RL, et al. Among authors: birch hl. Bioorg Med Chem Lett. 2008 Jan 15;18(2):629-33. doi: 10.1016/j.bmcl.2007.11.075. Epub 2007 Nov 28. Bioorg Med Chem Lett. 2008. PMID: 18068363

4

Development of CXCR3 antagonists. Part 3: Tropenyl and homotropenyl-piperidine urea derivatives.

Watson RJ, Allen DR, Birch HL, Chapman GA, Galvin FC, Jopling LA, Knight RL, Meier D, Oliver K, Meissner JW, Owen DA, Thomas EJ, Tremayne N, Williams SC. Watson RJ, et al. Among authors: birch hl. Bioorg Med Chem Lett. 2008 Jan 1;18(1):147-51. doi: 10.1016/j.bmcl.2007.10.109. Epub 2007 Nov 4. Bioorg Med Chem Lett. 2008. PMID: 18032038

5

Analysis of the pharmacokinetic/pharmacodynamic relationship of a small molecule CXCR3 antagonist, NBI-74330, using a murine CXCR3 internalization assay.

Jopling LA, Watt GF, Fisher S, Birch H, Coggon S, Christie MI. Jopling LA, et al. Br J Pharmacol. 2007 Dec;152(8):1260-71. doi: 10.1038/sj.bjp.0707519. Epub 2007 Nov 5. Br J Pharmacol. 2007. PMID: 17982480 Free PMC article.

6

CXCR3 antagonist NBI-74330 attenuates atherosclerotic plaque formation in LDL receptor-deficient mice.

van Wanrooij EJ, de Jager SC, van Es T, de Vos P, Birch HL, Owen DA, Watson RJ, Biessen EA, Chapman GA, van Berkel TJ, Kuiper J. van Wanrooij EJ, et al. Among authors: birch hl. Arterioscler Thromb Vasc Biol. 2008 Feb;28(2):251-7. doi: 10.1161/ATVBAHA.107.147827. Epub 2007 Nov 29. Arterioscler Thromb Vasc Biol. 2008. PMID: 18048768

7

Potent, Selective, and CNS-Penetrant Tetrasubstituted Cyclopropane Class IIa Histone Deacetylase (HDAC) Inhibitors.

Luckhurst CA, Breccia P, Stott AJ, Aziz O, Birch HL, Bürli RW, Hughes SJ, Jarvis RE, Lamers M, Leonard PM, Matthews KL, McAllister G, Pollack S, Saville-Stones E, Wishart G, Yates D, Dominguez C. Luckhurst CA, et al. Among authors: birch hl. ACS Med Chem Lett. 2015 Dec 10;7(1):34-9. doi: 10.1021/acsmedchemlett.5b00302. eCollection 2016 Jan 14. ACS Med Chem Lett. 2015. PMID: 26819662 Free PMC article.

8

Assessment of chloroquine treatment for modulating autophagy flux in brain of WT and HD mice.

Vodicka P, Lim J, Williams DT, Kegel KB, Chase K, Park H, Marchionini D, Wilkinson S, Mead T, Birch H, Yates D, Lyons K, Dominguez C, Beconi M, Yue Z, Aronin N, DiFiglia M. Vodicka P, et al. J Huntingtons Dis. 2014;3(2):159-74. doi: 10.3233/JHD-130081. J Huntingtons Dis. 2014. PMID: 25062859

9

Relative orientation of collagen molecules within a fibril: a homology model for homo sapiens type I collagen.

Collier TA, Nash A, Birch HL, de Leeuw NH. Collier TA, et al. Among authors: birch hl. J Biomol Struct Dyn. 2019 Feb;37(2):537-549. doi: 10.1080/07391102.2018.1433553. Epub 2018 Feb 15. J Biomol Struct Dyn. 2019. PMID: 29380684 Free article.

10

Effect on the mechanical properties of type I collagen of intra-molecular lysine-arginine derived advanced glycation end-product cross-linking.

Collier TA, Nash A, Birch HL, de Leeuw NH. Collier TA, et al. Among authors: birch hl. J Biomech. 2018 Jan 23;67:55-61. doi: 10.1016/j.jbiomech.2017.11.021. Epub 2017 Nov 28. J Biomech. 2018. PMID: 29254633 Free PMC article.

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