Norman BH - Search Results

1

Cyclohexyl-linked tricyclic isoxazoles are potent and selective modulators of the multidrug resistance protein (MRP1).

Norman BH, Lander PA, Gruber JM, Kroin JS, Cohen JD, Jungheim LN, Starling JJ, Law KL, Self TD, Tabas LB, Williams DC, Paul DC, Dantzig AH. Norman BH, et al. Bioorg Med Chem Lett. 2005 Dec 15;15(24):5526-30. doi: 10.1016/j.bmcl.2005.08.075. Epub 2005 Oct 3. Bioorg Med Chem Lett. 2005. PMID: 16202586

2

Tricyclic isoxazoles are novel inhibitors of the multidrug resistance protein (MRP1).

Norman BH, Gruber JM, Hollinshead SP, Wilson JW, Starling JJ, Law KL, Self TD, Tabas LB, Williams DC, Paul DC, Wagner MM, Dantzig AH. Norman BH, et al. Bioorg Med Chem Lett. 2002 Mar 25;12(6):883-6. doi: 10.1016/s0960-894x(02)00051-3. Bioorg Med Chem Lett. 2002. PMID: 11958985

3

Reversal of resistance in multidrug resistance protein (MRP1)-overexpressing cells by LY329146.

Norman BH, Dantzig AH, Kroin JS, Law KL, Tabas LB, Shepard RL, Palkowitz AD, Hauser KL, Winter MA, Sluka JP, Starling JJ. Norman BH, et al. Bioorg Med Chem Lett. 1999 Dec 6;9(23):3381-6. doi: 10.1016/s0960-894x(99)00610-1. Bioorg Med Chem Lett. 1999. PMID: 10612603

4

Pharmacological characterization of LY335979: a potent cyclopropyldibenzosuberane modulator of P-glycoprotein.

Starling JJ, Shepard RL, Cao J, Law KL, Norman BH, Kroin JS, Ehlhardt WJ, Baughman TM, Winter MA, Bell MG, Shih C, Gruber J, Elmquist WF, Dantzig AH. Starling JJ, et al. Among authors: norman bh. Adv Enzyme Regul. 1997;37:335-47. doi: 10.1016/s0065-2571(96)00021-0. Adv Enzyme Regul. 1997. PMID: 9381979

5

Identification of potent and selective retinoic acid receptor gamma (RARγ) antagonists for the treatment of osteoarthritis pain using structure based drug design.

Hughes NE, Bleisch TJ, Jones SA, Richardson TI, Doti RA, Wang Y, Stout SL, Durst GL, Chambers MG, Oskins JL, Lin C, Adams LA, Page TJ, Barr RJ, Zink RW, Osborne H, Montrose-Rafizadeh C, Norman BH. Hughes NE, et al. Among authors: norman bh. Bioorg Med Chem Lett. 2016 Jul 15;26(14):3274-3277. doi: 10.1016/j.bmcl.2016.05.056. Epub 2016 May 20. Bioorg Med Chem Lett. 2016. PMID: 27261179

6

Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 5: Combined A- and C-ring structure-activity relationship studies.

Richardson TI, Dodge JA, Wang Y, Durbin JD, Krishnan V, Norman BH. Richardson TI, et al. Among authors: norman bh. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5563-6. doi: 10.1016/j.bmcl.2007.08.009. Epub 2007 Aug 11. Bioorg Med Chem Lett. 2007. PMID: 17804226

7

Novel Autotaxin Inhibitors for the Treatment of Osteoarthritis Pain: Lead Optimization via Structure-Based Drug Design.

Jones SB, Pfeifer LA, Bleisch TJ, Beauchamp TJ, Durbin JD, Klimkowski VJ, Hughes NE, Rito CJ, Dao Y, Gruber JM, Bui H, Chambers MG, Chandrasekhar S, Lin C, McCann DJ, Mudra DR, Oskins JL, Swearingen CA, Thirunavukkarasu K, Norman BH. Jones SB, et al. Among authors: norman bh. ACS Med Chem Lett. 2016 Aug 2;7(9):857-61. doi: 10.1021/acsmedchemlett.6b00207. eCollection 2016 Sep 8. ACS Med Chem Lett. 2016. PMID: 27660691 Free PMC article.

8

Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 3: synthesis of cyclopentanone and cyclohexanone intermediates for C-ring modification.

Richardson TI, Dodge JA, Durst GL, Pfeifer LA, Shah J, Wang Y, Durbin JD, Krishnan V, Norman BH. Richardson TI, et al. Among authors: norman bh. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4824-8. doi: 10.1016/j.bmcl.2007.06.052. Epub 2007 Jun 20. Bioorg Med Chem Lett. 2007. PMID: 17614275

9

Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 2: structure-activity relationship studies on the benzopyran scaffold.

Richardson TI, Norman BH, Lugar CW, Jones SA, Wang Y, Durbin JD, Krishnan V, Dodge JA. Richardson TI, et al. Among authors: norman bh. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3570-4. doi: 10.1016/j.bmcl.2007.04.051. Epub 2007 Apr 25. Bioorg Med Chem Lett. 2007. PMID: 17485205

10

Characterization of 3,3-dimethyl substituted N-aryl piperidines as potent microsomal prostaglandin E synthase-1 inhibitors.

Kuklish SL, Antonysamy S, Bhattachar SN, Chandrasekhar S, Fisher MJ, Fretland AJ, Gooding K, Harvey A, Hughes NE, Luz JG, Manninen PR, McGee JE, Navarro A, Norman BH, Partridge KM, Quimby SJ, Schiffler MA, Sloan AV, Warshawsky AM, York JS, Yu XP. Kuklish SL, et al. Among authors: norman bh. Bioorg Med Chem Lett. 2016 Oct 1;26(19):4824-4828. doi: 10.1016/j.bmcl.2016.08.023. Epub 2016 Aug 10. Bioorg Med Chem Lett. 2016. PMID: 27554445

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