Monks BG - Search Results

1

The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.

Rothenfusser S, Goutagny N, DiPerna G, Gong M, Monks BG, Schoenemeyer A, Yamamoto M, Akira S, Fitzgerald KA. Rothenfusser S, et al. Among authors: monks bg. J Immunol. 2005 Oct 15;175(8):5260-8. doi: 10.4049/jimmunol.175.8.5260. J Immunol. 2005. PMID: 16210631

2

TLR9 signals after translocating from the ER to CpG DNA in the lysosome.

Latz E, Schoenemeyer A, Visintin A, Fitzgerald KA, Monks BG, Knetter CF, Lien E, Nilsen NJ, Espevik T, Golenbock DT. Latz E, et al. Among authors: monks bg. Nat Immunol. 2004 Feb;5(2):190-8. doi: 10.1038/ni1028. Epub 2004 Jan 11. Nat Immunol. 2004. PMID: 14716310

3

Cell type-specific recognition of human metapneumoviruses (HMPVs) by retinoic acid-inducible gene I (RIG-I) and TLR7 and viral interference of RIG-I ligand recognition by HMPV-B1 phosphoprotein.

Goutagny N, Jiang Z, Tian J, Parroche P, Schickli J, Monks BG, Ulbrandt N, Ji H, Kiener PA, Coyle AJ, Fitzgerald KA. Goutagny N, et al. Among authors: monks bg. J Immunol. 2010 Feb 1;184(3):1168-79. doi: 10.4049/jimmunol.0902750. Epub 2009 Dec 30. J Immunol. 2010. PMID: 20042593 Free PMC article.

4

LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.

Fitzgerald KA, Rowe DC, Barnes BJ, Caffrey DR, Visintin A, Latz E, Monks B, Pitha PM, Golenbock DT. Fitzgerald KA, et al. J Exp Med. 2003 Oct 6;198(7):1043-55. doi: 10.1084/jem.20031023. Epub 2003 Sep 29. J Exp Med. 2003. PMID: 14517278 Free PMC article.

5

Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid.

Conlon J, Burdette DL, Sharma S, Bhat N, Thompson M, Jiang Z, Rathinam VA, Monks B, Jin T, Xiao TS, Vogel SN, Vance RE, Fitzgerald KA. Conlon J, et al. J Immunol. 2013 May 15;190(10):5216-25. doi: 10.4049/jimmunol.1300097. Epub 2013 Apr 12. J Immunol. 2013. PMID: 23585680 Free PMC article.

6

The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction.

Rowe DC, McGettrick AF, Latz E, Monks BG, Gay NJ, Yamamoto M, Akira S, O'Neill LA, Fitzgerald KA, Golenbock DT. Rowe DC, et al. Among authors: monks bg. Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6299-304. doi: 10.1073/pnas.0510041103. Epub 2006 Apr 7. Proc Natl Acad Sci U S A. 2006. PMID: 16603631 Free PMC article.

7

A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling.

Nagpal K, Plantinga TS, Wong J, Monks BG, Gay NJ, Netea MG, Fitzgerald KA, Golenbock DT. Nagpal K, et al. Among authors: monks bg. J Biol Chem. 2009 Sep 18;284(38):25742-8. doi: 10.1074/jbc.M109.014886. Epub 2009 Jun 9. J Biol Chem. 2009. PMID: 19509286 Free PMC article.

8

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.

Bauernfeind FG, Horvath G, Stutz A, Alnemri ES, MacDonald K, Speert D, Fernandes-Alnemri T, Wu J, Monks BG, Fitzgerald KA, Hornung V, Latz E. Bauernfeind FG, et al. Among authors: monks bg. J Immunol. 2009 Jul 15;183(2):787-91. doi: 10.4049/jimmunol.0901363. Epub 2009 Jul 1. J Immunol. 2009. PMID: 19570822 Free PMC article.

9

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses.

Rathinam VA, Jiang Z, Waggoner SN, Sharma S, Cole LE, Waggoner L, Vanaja SK, Monks BG, Ganesan S, Latz E, Hornung V, Vogel SN, Szomolanyi-Tsuda E, Fitzgerald KA. Rathinam VA, et al. Among authors: monks bg. Nat Immunol. 2010 May;11(5):395-402. doi: 10.1038/ni.1864. Epub 2010 Mar 28. Nat Immunol. 2010. PMID: 20351692 Free PMC article.

10

Ligand-induced conformational changes allosterically activate Toll-like receptor 9.

Latz E, Verma A, Visintin A, Gong M, Sirois CM, Klein DC, Monks BG, McKnight CJ, Lamphier MS, Duprex WP, Espevik T, Golenbock DT. Latz E, et al. Among authors: monks bg. Nat Immunol. 2007 Jul;8(7):772-9. doi: 10.1038/ni1479. Epub 2007 Jun 17. Nat Immunol. 2007. PMID: 17572678

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