Jones SA - Search Results

1

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis.

Inagaki T, Choi M, Moschetta A, Peng L, Cummins CL, McDonald JG, Luo G, Jones SA, Goodwin B, Richardson JA, Gerard RD, Repa JJ, Mangelsdorf DJ, Kliewer SA. Inagaki T, et al. Among authors: jones sa. Cell Metab. 2005 Oct;2(4):217-25. doi: 10.1016/j.cmet.2005.09.001. Cell Metab. 2005. PMID: 16213224 Free article.

2

Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis.

Holt JA, Luo G, Billin AN, Bisi J, McNeill YY, Kozarsky KF, Donahee M, Wang DY, Mansfield TA, Kliewer SA, Goodwin B, Jones SA. Holt JA, et al. Among authors: jones sa. Genes Dev. 2003 Jul 1;17(13):1581-91. doi: 10.1101/gad.1083503. Epub 2003 Jun 18. Genes Dev. 2003. PMID: 12815072 Free PMC article.

3

Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta.

Janowski BA, Grogan MJ, Jones SA, Wisely GB, Kliewer SA, Corey EJ, Mangelsdorf DJ. Janowski BA, et al. Among authors: jones sa. Proc Natl Acad Sci U S A. 1999 Jan 5;96(1):266-71. doi: 10.1073/pnas.96.1.266. Proc Natl Acad Sci U S A. 1999. PMID: 9874807 Free PMC article.

4

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis.

Goodwin B, Jones SA, Price RR, Watson MA, McKee DD, Moore LB, Galardi C, Wilson JG, Lewis MC, Roth ME, Maloney PR, Willson TM, Kliewer SA. Goodwin B, et al. Among authors: jones sa. Mol Cell. 2000 Sep;6(3):517-26. doi: 10.1016/s1097-2765(00)00051-4. Mol Cell. 2000. PMID: 11030332 Free article.

5

Hepatoprotection by the farnesoid X receptor agonist GW4064 in rat models of intra- and extrahepatic cholestasis.

Liu Y, Binz J, Numerick MJ, Dennis S, Luo G, Desai B, MacKenzie KI, Mansfield TA, Kliewer SA, Goodwin B, Jones SA. Liu Y, et al. Among authors: jones sa. J Clin Invest. 2003 Dec;112(11):1678-87. doi: 10.1172/JCI18945. Epub 2003 Nov 17. J Clin Invest. 2003. PMID: 14623915 Free PMC article.

6

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway.

Kliewer SA, Moore JT, Wade L, Staudinger JL, Watson MA, Jones SA, McKee DD, Oliver BB, Willson TM, Zetterström RH, Perlmann T, Lehmann JM. Kliewer SA, et al. Among authors: jones sa. Cell. 1998 Jan 9;92(1):73-82. doi: 10.1016/s0092-8674(00)80900-9. Cell. 1998. PMID: 9489701 Free article.

7

Chemical genomics: functional analysis of orphan nuclear receptors in the regulation of bile acid metabolism.

Willson TM, Jones SA, Moore JT, Kliewer SA. Willson TM, et al. Among authors: jones sa. Med Res Rev. 2001 Nov;21(6):513-22. doi: 10.1002/med.1023. Med Res Rev. 2001. PMID: 11607932 Review.

8

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity.

Staudinger JL, Goodwin B, Jones SA, Hawkins-Brown D, MacKenzie KI, LaTour A, Liu Y, Klaassen CD, Brown KK, Reinhard J, Willson TM, Koller BH, Kliewer SA. Staudinger JL, et al. Among authors: jones sa. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3369-74. doi: 10.1073/pnas.051551698. Proc Natl Acad Sci U S A. 2001. PMID: 11248085 Free PMC article.

9

Use of in vitro pregnane X receptor assays to assess CYP3A4 induction potential of drug candidates.

Jones SA, Moore LB, Wisely GB, Kliewer SA. Jones SA, et al. Methods Enzymol. 2002;357:161-70. doi: 10.1016/s0076-6879(02)57675-8. Methods Enzymol. 2002. PMID: 12424907 No abstract available.

10

Cell-free ligand binding assays for nuclear receptors.

Jones SA, Parks DJ, Kliewer SA. Jones SA, et al. Methods Enzymol. 2003;364:53-71. doi: 10.1016/s0076-6879(03)64004-8. Methods Enzymol. 2003. PMID: 14631839

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