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The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy.
Höglinger GU, Lannuzel A, Khondiker ME, Michel PP, Duyckaerts C, Féger J, Champy P, Prigent A, Medja F, Lombes A, Oertel WH, Ruberg M, Hirsch EC. Höglinger GU, et al. Among authors: champy p. J Neurochem. 2005 Nov;95(4):930-9. doi: 10.1111/j.1471-4159.2005.03493.x. Epub 2005 Aug 10. J Neurochem. 2005. PMID: 16219024 Free article.
Annonacin, a lipophilic inhibitor of mitochondrial complex I, induces nigral and striatal neurodegeneration in rats: possible relevance for atypical parkinsonism in Guadeloupe.
Champy P, Höglinger GU, Féger J, Gleye C, Hocquemiller R, Laurens A, Guérineau V, Laprévote O, Medja F, Lombès A, Michel PP, Lannuzel A, Hirsch EC, Ruberg M. Champy P, et al. J Neurochem. 2004 Jan;88(1):63-9. doi: 10.1046/j.1471-4159.2003.02138.x. J Neurochem. 2004. PMID: 14675150 Free article.
Annonacin, a natural mitochondrial complex I inhibitor, causes tau pathology in cultured neurons.
Escobar-Khondiker M, Höllerhage M, Muriel MP, Champy P, Bach A, Depienne C, Respondek G, Yamada ES, Lannuzel A, Yagi T, Hirsch EC, Oertel WH, Jacob R, Michel PP, Ruberg M, Höglinger GU. Escobar-Khondiker M, et al. Among authors: champy p. J Neurosci. 2007 Jul 18;27(29):7827-37. doi: 10.1523/JNEUROSCI.1644-07.2007. J Neurosci. 2007. PMID: 17634376 Free PMC article.
Annonacin, a natural lipophilic mitochondrial complex I inhibitor, increases phosphorylation of tau in the brain of FTDP-17 transgenic mice.
Yamada ES, Respondek G, Müssner S, de Andrade A, Höllerhage M, Depienne C, Rastetter A, Tarze A, Friguet B, Salama M, Champy P, Oertel WH, Höglinger GU. Yamada ES, et al. Among authors: champy p. Exp Neurol. 2014 Mar;253:113-25. doi: 10.1016/j.expneurol.2013.12.017. Epub 2014 Jan 3. Exp Neurol. 2014. PMID: 24389273 Free article.
Chronic consumption of Annona muricata juice triggers and aggravates cerebral tau phosphorylation in wild-type and MAPT transgenic mice.
Rottscholl R, Haegele M, Jainsch B, Xu H, Respondek G, Höllerhage M, Rösler TW, Bony E, Le Ven J, Guérineau V, Schmitz-Afonso I, Champy P, Oertel WH, Yamada ES, Höglinger GU. Rottscholl R, et al. Among authors: champy p. J Neurochem. 2016 Nov;139(4):624-639. doi: 10.1111/jnc.13835. Epub 2016 Sep 16. J Neurochem. 2016. PMID: 27569447 Free article.
67 results