Wielinga PR - Search Results

1

Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides.

Zelcer N, van de Wetering K, de Waart R, Scheffer GL, Marschall HU, Wielinga PR, Kuil A, Kunne C, Smith A, van der Valk M, Wijnholds J, Elferink RO, Borst P. Zelcer N, et al. Among authors: wielinga pr. J Hepatol. 2006 Apr;44(4):768-75. doi: 10.1016/j.jhep.2005.07.022. Epub 2005 Aug 9. J Hepatol. 2006. PMID: 16225954

2

Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception.

Zelcer N, van de Wetering K, Hillebrand M, Sarton E, Kuil A, Wielinga PR, Tephly T, Dahan A, Beijnen JH, Borst P. Zelcer N, et al. Among authors: wielinga pr. Proc Natl Acad Sci U S A. 2005 May 17;102(20):7274-9. doi: 10.1073/pnas.0502530102. Epub 2005 May 10. Proc Natl Acad Sci U S A. 2005. PMID: 15886284 Free PMC article.

3

Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4).

Zelcer N, Reid G, Wielinga P, Kuil A, van der Heijden I, Schuetz JD, Borst P. Zelcer N, et al. Biochem J. 2003 Apr 15;371(Pt 2):361-7. doi: 10.1042/BJ20021886. Biochem J. 2003. PMID: 12523936 Free PMC article.

4

The potential impact of drug transporters on nucleoside-analog-based antiviral chemotherapy.

Borst P, Balzarini J, Ono N, Reid G, de Vries H, Wielinga P, Wijnholds J, Zelcer N. Borst P, et al. Antiviral Res. 2004 Apr;62(1):1-7. doi: 10.1016/j.antiviral.2003.11.002. Antiviral Res. 2004. PMID: 15026196 Review.

5

Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells.

Wielinga PR, van der Heijden I, Reid G, Beijnen JH, Wijnholds J, Borst P. Wielinga PR, et al. J Biol Chem. 2003 May 16;278(20):17664-71. doi: 10.1074/jbc.M212723200. Epub 2003 Mar 13. J Biol Chem. 2003. PMID: 12637526 Free article.

6

cGMP transport by vesicles from human and mouse erythrocytes.

de Wolf CJ, Yamaguchi H, van der Heijden I, Wielinga PR, Hundscheid SL, Ono N, Scheffer GL, de Haas M, Schuetz JD, Wijnholds J, Borst P. de Wolf CJ, et al. Among authors: wielinga pr. FEBS J. 2007 Jan;274(2):439-50. doi: 10.1111/j.1742-4658.2006.05591.x. FEBS J. 2007. PMID: 17229149 Free article.

7

Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5.

Reid G, Wielinga P, Zelcer N, De Haas M, Van Deemter L, Wijnholds J, Balzarini J, Borst P. Reid G, et al. Mol Pharmacol. 2003 May;63(5):1094-103. doi: 10.1124/mol.63.5.1094. Mol Pharmacol. 2003. PMID: 12695538

8

Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2).

Zelcer N, Huisman MT, Reid G, Wielinga P, Breedveld P, Kuil A, Knipscheer P, Schellens JH, Schinkel AH, Borst P. Zelcer N, et al. J Biol Chem. 2003 Jun 27;278(26):23538-44. doi: 10.1074/jbc.M303504200. Epub 2003 Apr 17. J Biol Chem. 2003. PMID: 12702717 Free article.

9

The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs.

Reid G, Wielinga P, Zelcer N, van der Heijden I, Kuil A, de Haas M, Wijnholds J, Borst P. Reid G, et al. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9244-9. doi: 10.1073/pnas.1033060100. Epub 2003 Jun 30. Proc Natl Acad Sci U S A. 2003. PMID: 12835412 Free PMC article.

10

The human multidrug resistance protein MRP5 transports folates and can mediate cellular resistance against antifolates.

Wielinga P, Hooijberg JH, Gunnarsdottir S, Kathmann I, Reid G, Zelcer N, van der Born K, de Haas M, van der Heijden I, Kaspers G, Wijnholds J, Jansen G, Peters G, Borst P. Wielinga P, et al. Cancer Res. 2005 May 15;65(10):4425-30. doi: 10.1158/0008-5472.CAN-04-2810. Cancer Res. 2005. PMID: 15899835

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