Weatherall DJ - Search Results

1

Negative epistasis between the malaria-protective effects of alpha+-thalassemia and the sickle cell trait.

Williams TN, Mwangi TW, Wambua S, Peto TE, Weatherall DJ, Gupta S, Recker M, Penman BS, Uyoga S, Macharia A, Mwacharo JK, Snow RW, Marsh K. Williams TN, et al. Among authors: weatherall dj. Nat Genet. 2005 Nov;37(11):1253-7. doi: 10.1038/ng1660. Epub 2005 Oct 16. Nat Genet. 2005. PMID: 16227994 Free PMC article. Clinical Trial.

2

An immune basis for malaria protection by the sickle cell trait.

Williams TN, Mwangi TW, Roberts DJ, Alexander ND, Weatherall DJ, Wambua S, Kortok M, Snow RW, Marsh K. Williams TN, et al. Among authors: weatherall dj. PLoS Med. 2005 May;2(5):e128. doi: 10.1371/journal.pmed.0020128. Epub 2005 May 31. PLoS Med. 2005. PMID: 15916466 Free PMC article.

3

The effect of alpha+-thalassaemia on the incidence of malaria and other diseases in children living on the coast of Kenya.

Wambua S, Mwangi TW, Kortok M, Uyoga SM, Macharia AW, Mwacharo JK, Weatherall DJ, Snow RW, Marsh K, Williams TN. Wambua S, et al. Among authors: weatherall dj. PLoS Med. 2006 May;3(5):e158. doi: 10.1371/journal.pmed.0030158. Epub 2006 Apr 18. PLoS Med. 2006. PMID: 16605300 Free PMC article.

4

The membrane characteristics of Plasmodium falciparum-infected and -uninfected heterozygous alpha(0)thalassaemic erythrocytes.

Williams TN, Weatherall DJ, Newbold CI. Williams TN, et al. Among authors: weatherall dj. Br J Haematol. 2002 Aug;118(2):663-70. doi: 10.1046/j.1365-2141.2002.03610.x. Br J Haematol. 2002. PMID: 12139762 Free article.

5

Epistatic interactions between genetic disorders of hemoglobin can explain why the sickle-cell gene is uncommon in the Mediterranean.

Penman BS, Pybus OG, Weatherall DJ, Gupta S. Penman BS, et al. Among authors: weatherall dj. Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21242-6. doi: 10.1073/pnas.0910840106. Epub 2009 Dec 1. Proc Natl Acad Sci U S A. 2009. PMID: 19955437 Free PMC article.

6

World distribution, population genetics, and health burden of the hemoglobinopathies.

Williams TN, Weatherall DJ. Williams TN, et al. Among authors: weatherall dj. Cold Spring Harb Perspect Med. 2012 Sep 1;2(9):a011692. doi: 10.1101/cshperspect.a011692. Cold Spring Harb Perspect Med. 2012. PMID: 22951448 Free PMC article. Review.

7

High incidence of malaria in alpha-thalassaemic children.

Williams TN, Maitland K, Bennett S, Ganczakowski M, Peto TE, Newbold CI, Bowden DK, Weatherall DJ, Clegg JB. Williams TN, et al. Among authors: weatherall dj. Nature. 1996 Oct 10;383(6600):522-5. doi: 10.1038/383522a0. Nature. 1996. PMID: 8849722

8

Global distribution of the sickle cell gene and geographical confirmation of the malaria hypothesis.

Piel FB, Patil AP, Howes RE, Nyangiri OA, Gething PW, Williams TN, Weatherall DJ, Hay SI. Piel FB, et al. Among authors: weatherall dj. Nat Commun. 2010 Nov 2;1:104. doi: 10.1038/ncomms1104. Nat Commun. 2010. PMID: 21045822 Free PMC article.

9

Global burden of sickle cell anaemia in children under five, 2010-2050: modelling based on demographics, excess mortality, and interventions.

Piel FB, Hay SI, Gupta S, Weatherall DJ, Williams TN. Piel FB, et al. Among authors: weatherall dj. PLoS Med. 2013;10(7):e1001484. doi: 10.1371/journal.pmed.1001484. Epub 2013 Jul 16. PLoS Med. 2013. PMID: 23874164 Free PMC article.

10

alpha+-Thalassemia protects children against disease caused by other infections as well as malaria.

Allen SJ, O'Donnell A, Alexander ND, Alpers MP, Peto TE, Clegg JB, Weatherall DJ. Allen SJ, et al. Among authors: weatherall dj. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14736-41. doi: 10.1073/pnas.94.26.14736. Proc Natl Acad Sci U S A. 1997. PMID: 9405682 Free PMC article.

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