Bruns C - Search Results

1

Design and preparation of 2-benzamido-pyrimidines as inhibitors of IKK.

Waelchli R, Bollbuck B, Bruns C, Buhl T, Eder J, Feifel R, Hersperger R, Janser P, Revesz L, Zerwes HG, Schlapbach A. Waelchli R, et al. Among authors: bruns c. Bioorg Med Chem Lett. 2006 Jan 1;16(1):108-12. doi: 10.1016/j.bmcl.2005.09.035. Epub 2005 Oct 19. Bioorg Med Chem Lett. 2006. PMID: 16236504

2

A potent and selective S1P(1) antagonist with efficacy in experimental autoimmune encephalomyelitis.

Quancard J, Bollbuck B, Janser P, Angst D, Berst F, Buehlmayer P, Streiff M, Beerli C, Brinkmann V, Guerini D, Smith PA, Seabrook TJ, Traebert M, Seuwen K, Hersperger R, Bruns C, Bassilana F, Bigaud M. Quancard J, et al. Among authors: bruns c. Chem Biol. 2012 Sep 21;19(9):1142-51. doi: 10.1016/j.chembiol.2012.07.016. Chem Biol. 2012. PMID: 22999882

3

An oral sphingosine 1-phosphate receptor 1 (S1P(1)) antagonist prodrug with efficacy in vivo: discovery, synthesis, and evaluation.

Angst D, Janser P, Quancard J, Buehlmayer P, Berst F, Oberer L, Beerli C, Streiff M, Pally C, Hersperger R, Bruns C, Bassilana F, Bollbuck B. Angst D, et al. Among authors: bruns c. J Med Chem. 2012 Nov 26;55(22):9722-34. doi: 10.1021/jm3009508. Epub 2012 Oct 26. J Med Chem. 2012. PMID: 23067318

4

Pathophysiological Consequences of a Break in S1P1-Dependent Homeostasis of Vascular Permeability Revealed by S1P1 Competitive Antagonism.

Bigaud M, Dincer Z, Bollbuck B, Dawson J, Beckmann N, Beerli C, Fishli-Cavelti G, Nahler M, Angst D, Janser P, Otto H, Rosner E, Hersperger R, Bruns C, Quancard J. Bigaud M, et al. Among authors: bruns c. PLoS One. 2016 Dec 22;11(12):e0168252. doi: 10.1371/journal.pone.0168252. eCollection 2016. PLoS One. 2016. PMID: 28005953 Free PMC article.

5

Pyrazole derived from (+)-3-carene; a novel potent, selective scaffold for sphingosine-1-phosphate (S1P(1)) receptor agonists.

Zécri FJ, Albert R, Landrum G, Hinterding K, Cooke NG, Guerini D, Streiff M, Bruns C, Nuesslein-Hildesheim B. Zécri FJ, et al. Among authors: bruns c. Bioorg Med Chem Lett. 2010 Jan 1;20(1):35-7. doi: 10.1016/j.bmcl.2009.11.045. Epub 2009 Nov 15. Bioorg Med Chem Lett. 2010. PMID: 19954976

6

Transplantation-induced functional/morphological changes in rat aorta allografts differ from those in arteries of rat kidney allografts.

Andriambeloson E, Cannet C, Pally C, Klanke B, Bruns C, Zerwes HG, Bigaud M. Andriambeloson E, et al. Among authors: bruns c. Am J Transplant. 2004 Feb;4(2):188-95. doi: 10.1046/j.1600-6143.2003.00319.x. Am J Transplant. 2004. PMID: 14974939 Free article.

7

A novel somatostatin mimic with broad somatotropin release inhibitory factor receptor binding and superior therapeutic potential.

Lewis I, Bauer W, Albert R, Chandramouli N, Pless J, Weckbecker G, Bruns C. Lewis I, et al. Among authors: bruns c. J Med Chem. 2003 Jun 5;46(12):2334-44. doi: 10.1021/jm021093t. J Med Chem. 2003. PMID: 12773038

8

Transplantation-induced endothelial dysfunction as studied in rat aorta allografts.

Andriambeloson E, Pally C, Hengerer B, Cannet C, Nikolova Z, Bruns C, Zerwes HG, Bigaud M. Andriambeloson E, et al. Among authors: bruns c. Transplantation. 2001 Dec 27;72(12):1881-9. doi: 10.1097/00007890-200112270-00004. Transplantation. 2001. PMID: 11773884

9

Synthesis and biological evaluation of a potent E-selectin antagonist.

Thoma G, Kinzy W, Bruns C, Patton JT, Magnani JL, Bänteli R. Thoma G, et al. Among authors: bruns c. J Med Chem. 1999 Nov 18;42(23):4909-13. doi: 10.1021/jm990422n. J Med Chem. 1999. PMID: 10579852

10

Transplantation-induced ischemia/reperfusion injury in the rat heart.

Bigaud M, Gfeller P, Deveze S, Vogt G, Evenou JP, Bruns C, Zerwes HG. Bigaud M, et al. Among authors: bruns c. Transplant Proc. 1998 Aug;30(5):2311-3. doi: 10.1016/s0041-1345(98)00635-6. Transplant Proc. 1998. PMID: 9723486 No abstract available.

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