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Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans.
Ved R, Saha S, Westlund B, Perier C, Burnam L, Sluder A, Hoener M, Rodrigues CM, Alfonso A, Steer C, Liu L, Przedborski S, Wolozin B. Ved R, et al. Among authors: hoener m. J Biol Chem. 2005 Dec 30;280(52):42655-42668. doi: 10.1074/jbc.M505910200. Epub 2005 Oct 19. J Biol Chem. 2005. PMID: 16239214 Free PMC article.
Trace amine-associated receptor 1 partial agonism reveals novel paradigm for neuropsychiatric therapeutics.
Revel FG, Moreau JL, Gainetdinov RR, Ferragud A, Velázquez-Sánchez C, Sotnikova TD, Morairty SR, Harmeier A, Groebke Zbinden K, Norcross RD, Bradaia A, Kilduff TS, Biemans B, Pouzet B, Caron MG, Canales JJ, Wallace TL, Wettstein JG, Hoener MC. Revel FG, et al. Biol Psychiatry. 2012 Dec 1;72(11):934-42. doi: 10.1016/j.biopsych.2012.05.014. Epub 2012 Jun 16. Biol Psychiatry. 2012. PMID: 22705041
Trace amine-associated receptor 1 modulates dopaminergic activity.
Lindemann L, Meyer CA, Jeanneau K, Bradaia A, Ozmen L, Bluethmann H, Bettler B, Wettstein JG, Borroni E, Moreau JL, Hoener MC. Lindemann L, et al. J Pharmacol Exp Ther. 2008 Mar;324(3):948-56. doi: 10.1124/jpet.107.132647. Epub 2007 Dec 14. J Pharmacol Exp Ther. 2008. PMID: 18083911
G protein-coupled receptor transmembrane binding pockets and their applications in GPCR research and drug discovery: a survey.
Kratochwil NA, Gatti-McArthur S, Hoener MC, Lindemann L, Christ AD, Green LG, Guba W, Martin RE, Malherbe P, Porter RH, Slack JP, Winnig M, Dehmlow H, Grether U, Hertel C, Narquizian R, Panousis CG, Kolczewski S, Steward L. Kratochwil NA, et al. Among authors: hoener mc. Curr Top Med Chem. 2011;11(15):1902-24. doi: 10.2174/156802611796391267. Curr Top Med Chem. 2011. PMID: 21470172
TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity.
Revel FG, Moreau JL, Gainetdinov RR, Bradaia A, Sotnikova TD, Mory R, Durkin S, Zbinden KG, Norcross R, Meyer CA, Metzler V, Chaboz S, Ozmen L, Trube G, Pouzet B, Bettler B, Caron MG, Wettstein JG, Hoener MC. Revel FG, et al. Proc Natl Acad Sci U S A. 2011 May 17;108(20):8485-90. doi: 10.1073/pnas.1103029108. Epub 2011 Apr 27. Proc Natl Acad Sci U S A. 2011. PMID: 21525407 Free PMC article.
113 results