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An in vitro toolbox to accelerate anti-malarial drug discovery and development.
Charman SA, Andreu A, Barker H, Blundell S, Campbell A, Campbell M, Chen G, Chiu FCK, Crighton E, Katneni K, Morizzi J, Patil R, Pham T, Ryan E, Saunders J, Shackleford DM, White KL, Almond L, Dickins M, Smith DA, Moehrle JJ, Burrows JN, Abla N. Charman SA, et al. Among authors: abla n. Malar J. 2020 Jan 2;19(1):1. doi: 10.1186/s12936-019-3075-5. Malar J. 2020. PMID: 31898492 Free PMC article.
Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439.
Shackleford DM, Chiu FCK, Katneni K, Blundell S, McLaren J, Wang X, Zhou L, Sriraghavan K, Alker AM, Hunziker D, Scheurer C, Zhao Q, Dong Y, Möhrle JJ, Abla N, Matile H, Wittlin S, Vennerstrom JL, Charman SA. Shackleford DM, et al. Among authors: abla n. ACS Infect Dis. 2021 Jul 9;7(7):1885-1893. doi: 10.1021/acsinfecdis.1c00225. Epub 2021 Jun 8. ACS Infect Dis. 2021. PMID: 34101429 Free PMC article.
Long-Lasting and Fast-Acting in Vivo Efficacious Antiplasmodial Azepanylcarbazole Amino Alcohol.
Abla N, Bashyam S, Charman SA, Greco B, Hewitt P, Jiménez-Díaz MB, Katneni K, Kubas H, Picard D, Sambandan Y, Sanz L, Smith D, Wang T, Willis P, Wittlin S, Spangenberg T. Abla N, et al. ACS Med Chem Lett. 2017 Nov 28;8(12):1304-1308. doi: 10.1021/acsmedchemlett.7b00391. eCollection 2017 Dec 14. ACS Med Chem Lett. 2017. PMID: 29259752 Free PMC article.
27 results