Durgam GG - Search Results

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Synthesis and pharmacological evaluation of second-generation phosphatidic acid derivatives as lysophosphatidic acid receptor ligands.

Durgam GG, Tsukahara R, Makarova N, Walker MD, Fujiwara Y, Pigg KR, Baker DL, Sardar VM, Parrill AL, Tigyi G, Miller DD. Durgam GG, et al. Bioorg Med Chem Lett. 2006 Feb;16(3):633-40. doi: 10.1016/j.bmcl.2005.10.031. Epub 2005 Nov 2. Bioorg Med Chem Lett. 2006. PMID: 16263282

Synthesis and biological evaluation of novel cytotoxic phospholipids for prostate cancer.

Gududuru V, Hurh E, Durgam GG, Hong SS, Sardar VM, Xu H, Dalton JT, Miller DD. Gududuru V, et al. Among authors: durgam gg. Bioorg Med Chem Lett. 2004 Oct 4;14(19):4919-23. doi: 10.1016/j.bmcl.2004.07.026. Bioorg Med Chem Lett. 2004. PMID: 15341952

Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of PPARgamma, and inhibitors of autotaxin.

Durgam GG, Virag T, Walker MD, Tsukahara R, Yasuda S, Liliom K, van Meeteren LA, Moolenaar WH, Wilke N, Siess W, Tigyi G, Miller DD. Durgam GG, et al. J Med Chem. 2005 Jul 28;48(15):4919-30. doi: 10.1021/jm049609r. J Med Chem. 2005. PMID: 16033271

Fatty alcohol phosphates are subtype-selective agonists and antagonists of lysophosphatidic acid receptors.

Virag T, Elrod DB, Liliom K, Sardar VM, Parrill AL, Yokoyama K, Durgam G, Deng W, Miller DD, Tigyi G. Virag T, et al. Mol Pharmacol. 2003 May;63(5):1032-42. doi: 10.1124/mol.63.5.1032. Mol Pharmacol. 2003. PMID: 12695531

The lysophosphatidic acid type 2 receptor is required for protection against radiation-induced intestinal injury.

Deng W, Shuyu E, Tsukahara R, Valentine WJ, Durgam G, Gududuru V, Balazs L, Manickam V, Arsura M, VanMiddlesworth L, Johnson LR, Parrill AL, Miller DD, Tigyi G. Deng W, et al. Gastroenterology. 2007 May;132(5):1834-51. doi: 10.1053/j.gastro.2007.03.038. Epub 2007 Mar 24. Gastroenterology. 2007. PMID: 17484878 Free PMC article.

Lysophosphatidic acid-induced platelet shape change revealed through LPA(1-5) receptor-selective probes and albumin.

Khandoga AL, Fujiwara Y, Goyal P, Pandey D, Tsukahara R, Bolen A, Guo H, Wilke N, Liu J, Valentine WJ, Durgam GG, Miller DD, Jiang G, Prestwich GD, Tigyi G, Siess W. Khandoga AL, et al. Among authors: durgam gg. Platelets. 2008 Sep;19(6):415-27. doi: 10.1080/09537100802220468. Platelets. 2008. PMID: 18925509 Free PMC article.

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