Sargin B - Search Results

1

Constitutive activation of Akt by Flt3 internal tandem duplications is necessary for increased survival, proliferation, and myeloid transformation.

Brandts CH, Sargin B, Rode M, Biermann C, Lindtner B, Schwäble J, Buerger H, Müller-Tidow C, Choudhary C, McMahon M, Berdel WE, Serve H. Brandts CH, et al. Among authors: sargin b. Cancer Res. 2005 Nov 1;65(21):9643-50. doi: 10.1158/0008-5472.CAN-05-0422. Cancer Res. 2005. PMID: 16266983

2

Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations.

Mizuki M, Schwable J, Steur C, Choudhary C, Agrawal S, Sargin B, Steffen B, Matsumura I, Kanakura Y, Böhmer FD, Müller-Tidow C, Berdel WE, Serve H. Mizuki M, et al. Among authors: sargin b. Blood. 2003 Apr 15;101(8):3164-73. doi: 10.1182/blood-2002-06-1677. Epub 2002 Dec 5. Blood. 2003. PMID: 12468433 Free article.

3

RGS2 is an important target gene of Flt3-ITD mutations in AML and functions in myeloid differentiation and leukemic transformation.

Schwäble J, Choudhary C, Thiede C, Tickenbrock L, Sargin B, Steur C, Rehage M, Rudat A, Brandts C, Berdel WE, Müller-Tidow C, Serve H. Schwäble J, et al. Among authors: sargin b. Blood. 2005 Mar 1;105(5):2107-14. doi: 10.1182/blood-2004-03-0940. Epub 2004 Nov 9. Blood. 2005. PMID: 15536149 Free article.

4

Flt3 tandem duplication mutations cooperate with Wnt signaling in leukemic signal transduction.

Tickenbrock L, Schwäble J, Wiedehage M, Steffen B, Sargin B, Choudhary C, Brandts C, Berdel WE, Müller-Tidow C, Serve H. Tickenbrock L, et al. Among authors: sargin b. Blood. 2005 May 1;105(9):3699-706. doi: 10.1182/blood-2004-07-2924. Epub 2005 Jan 13. Blood. 2005. PMID: 15650056 Free article.

5

AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations.

Choudhary C, Schwäble J, Brandts C, Tickenbrock L, Sargin B, Kindler T, Fischer T, Berdel WE, Müller-Tidow C, Serve H. Choudhary C, et al. Among authors: sargin b. Blood. 2005 Jul 1;106(1):265-73. doi: 10.1182/blood-2004-07-2942. Epub 2005 Mar 15. Blood. 2005. PMID: 15769897 Free article.

6

Activation mechanisms of STAT5 by oncogenic Flt3-ITD.

Choudhary C, Brandts C, Schwable J, Tickenbrock L, Sargin B, Ueker A, Böhmer FD, Berdel WE, Müller-Tidow C, Serve H. Choudhary C, et al. Among authors: sargin b. Blood. 2007 Jul 1;110(1):370-4. doi: 10.1182/blood-2006-05-024018. Epub 2007 Mar 13. Blood. 2007. PMID: 17356133 Free article.

7

Flt3-dependent transformation by inactivating c-Cbl mutations in AML.

Sargin B, Choudhary C, Crosetto N, Schmidt MHH, Grundler R, Rensinghoff M, Thiessen C, Tickenbrock L, Schwäble J, Brandts C, August B, Koschmieder S, Bandi SR, Duyster J, Berdel WE, Müller-Tidow C, Dikic I, Serve H. Sargin B, et al. Blood. 2007 Aug 1;110(3):1004-12. doi: 10.1182/blood-2007-01-066076. Epub 2007 Apr 19. Blood. 2007. PMID: 17446348 Free article. Clinical Trial.

8

Activation of Wnt signaling in cKit-ITD mediated transformation and imatinib sensitivity in acute myeloid leukemia.

Tickenbrock L, Hehn S, Sargin B, Evers G, Ng PR, Choudhary C, Berdel WE, Müller-Tidow C, Serve H. Tickenbrock L, et al. Among authors: sargin b. Int J Hematol. 2008 Sep;88(2):174-180. doi: 10.1007/s12185-008-0141-0. Epub 2008 Jul 31. Int J Hematol. 2008. PMID: 18668305

9

Activation of Wnt signalling in acute myeloid leukemia by induction of Frizzled-4.

Tickenbrock L, Hehn S, Sargin B, Choudhary C, Bäumer N, Buerger H, Schulte B, Müller O, Berdel WE, Müller-Tidow C, Serve H. Tickenbrock L, et al. Among authors: sargin b. Int J Oncol. 2008 Dec;33(6):1215-21. Int J Oncol. 2008. PMID: 19020754

10

Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.

Müller-Tidow C, Steffen B, Cauvet T, Tickenbrock L, Ji P, Diederichs S, Sargin B, Köhler G, Stelljes M, Puccetti E, Ruthardt M, deVos S, Hiebert SW, Koeffler HP, Berdel WE, Serve H. Müller-Tidow C, et al. Among authors: sargin b. Mol Cell Biol. 2004 Apr;24(7):2890-904. doi: 10.1128/MCB.24.7.2890-2904.2004. Mol Cell Biol. 2004. PMID: 15024077 Free PMC article.

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