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Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia.
Konopleva M, Contractor R, Tsao T, Samudio I, Ruvolo PP, Kitada S, Deng X, Zhai D, Shi YX, Sneed T, Verhaegen M, Soengas M, Ruvolo VR, McQueen T, Schober WD, Watt JC, Jiffar T, Ling X, Marini FC, Harris D, Dietrich M, Estrov Z, McCubrey J, May WS, Reed JC, Andreeff M. Konopleva M, et al. Among authors: contractor r. Cancer Cell. 2006 Nov;10(5):375-88. doi: 10.1016/j.ccr.2006.10.006. Cancer Cell. 2006. PMID: 17097560 Free article.
PPARgamma-active triterpenoid CDDO enhances ATRA-induced differentiation in APL.
Tabe Y, Konopleva M, Kondo Y, Contractor R, Tsao T, Konoplev S, Shi Y, Ling X, Watt JC, Tsutsumi-Ishii Y, Ohsaka A, Nagaoka I, Issa JP, Kogan SC, Andreeff M. Tabe Y, et al. Among authors: contractor r. Cancer Biol Ther. 2007 Dec;6(12):1967-77. doi: 10.4161/cbt.6.12.4982. Epub 2007 Sep 4. Cancer Biol Ther. 2007. PMID: 18075297 Free article.
Targeted therapy of AML new concepts.
Andreeff M, Milella M, Carter BZ, Tabe Y, Ricciardi MR, Sneed T, Ruvolo P, Contractor R, Tsao T, Schober W, Evans R, McQueen T, Zeng Z, Kornblau SM, McCubrey J, Estey E, Mills GB, Reed JC, Konopleva M. Andreeff M, et al. Among authors: contractor r. Ann Hematol. 2004;83 Suppl 1:S51-3. doi: 10.1007/s00277-004-0849-8. Ann Hematol. 2004. PMID: 15124670 No abstract available.
A novel mechanism of action of methyl-2-cyano-3,12 dioxoolean-1,9 diene-28-oate: direct permeabilization of the inner mitochondrial membrane to inhibit electron transport and induce apoptosis.
Samudio I, Konopleva M, Pelicano H, Huang P, Frolova O, Bornmann W, Ying Y, Evans R, Contractor R, Andreeff M. Samudio I, et al. Among authors: contractor r. Mol Pharmacol. 2006 Apr;69(4):1182-93. doi: 10.1124/mol.105.018051. Epub 2006 Jan 12. Mol Pharmacol. 2006. PMID: 16410408
36 results