Stapleton D - Search Results

1

Increased alpha2 subunit-associated AMPK activity and PRKAG2 cardiomyopathy.

Ahmad F, Arad M, Musi N, He H, Wolf C, Branco D, Perez-Atayde AR, Stapleton D, Bali D, Xing Y, Tian R, Goodyear LJ, Berul CI, Ingwall JS, Seidman CE, Seidman JG. Ahmad F, et al. Among authors: stapleton d. Circulation. 2005 Nov 15;112(20):3140-8. doi: 10.1161/CIRCULATIONAHA.105.550806. Epub 2005 Nov 7. Circulation. 2005. PMID: 16275868

2

Transgenic mice overexpressing mutant PRKAG2 define the cause of Wolff-Parkinson-White syndrome in glycogen storage cardiomyopathy.

Arad M, Moskowitz IP, Patel VV, Ahmad F, Perez-Atayde AR, Sawyer DB, Walter M, Li GH, Burgon PG, Maguire CT, Stapleton D, Schmitt JP, Guo XX, Pizard A, Kupershmidt S, Roden DM, Berul CI, Seidman CE, Seidman JG. Arad M, et al. Among authors: stapleton d. Circulation. 2003 Jun 10;107(22):2850-6. doi: 10.1161/01.CIR.0000075270.13497.2B. Epub 2003 Jun 2. Circulation. 2003. PMID: 12782567

3

AMPK beta subunit targets metabolic stress sensing to glycogen.

Polekhina G, Gupta A, Michell BJ, van Denderen B, Murthy S, Feil SC, Jennings IG, Campbell DJ, Witters LA, Parker MW, Kemp BE, Stapleton D. Polekhina G, et al. Among authors: stapleton d. Curr Biol. 2003 May 13;13(10):867-71. doi: 10.1016/s0960-9822(03)00292-6. Curr Biol. 2003. PMID: 12747837 Free article.

4

Mutations in the gal83 glycogen-binding domain activate the snf1/gal83 kinase pathway by a glycogen-independent mechanism.

Wiatrowski HA, Van Denderen BJ, Berkey CD, Kemp BE, Stapleton D, Carlson M. Wiatrowski HA, et al. Among authors: stapleton d. Mol Cell Biol. 2004 Jan;24(1):352-61. doi: 10.1128/MCB.24.1.352-361.2004. Mol Cell Biol. 2004. PMID: 14673168 Free PMC article.

5

Reduced glycogen availability is associated with increased AMPKalpha2 activity, nuclear AMPKalpha2 protein abundance, and GLUT4 mRNA expression in contracting human skeletal muscle.

Steinberg GR, Watt MJ, McGee SL, Chan S, Hargreaves M, Febbraio MA, Stapleton D, Kemp BE. Steinberg GR, et al. Among authors: stapleton d. Appl Physiol Nutr Metab. 2006 Jun;31(3):302-12. doi: 10.1139/h06-003. Appl Physiol Nutr Metab. 2006. PMID: 16770359

6

Post-translational modifications of the beta-1 subunit of AMP-activated protein kinase affect enzyme activity and cellular localization.

Warden SM, Richardson C, O'Donnell J Jr, Stapleton D, Kemp BE, Witters LA. Warden SM, et al. Among authors: stapleton d. Biochem J. 2001 Mar 1;354(Pt 2):275-83. doi: 10.1042/0264-6021:3540275. Biochem J. 2001. PMID: 11171104 Free PMC article.

7

The recruitment of AMP-activated protein kinase to glycogen is regulated by autophosphorylation.

Oligschlaeger Y, Miglianico M, Chanda D, Scholz R, Thali RF, Tuerk R, Stapleton DI, Gooley PR, Neumann D. Oligschlaeger Y, et al. Among authors: stapleton di. J Biol Chem. 2015 May 1;290(18):11715-28. doi: 10.1074/jbc.M114.633271. Epub 2015 Mar 19. J Biol Chem. 2015. PMID: 25792737 Free PMC article.

8

When phosphorylated at Thr148, the β2-subunit of AMP-activated kinase does not associate with glycogen in skeletal muscle.

Xu H, Frankenberg NT, Lamb GD, Gooley PR, Stapleton DI, Murphy RM. Xu H, et al. Among authors: stapleton di. Am J Physiol Cell Physiol. 2016 Jul 1;311(1):C35-42. doi: 10.1152/ajpcell.00047.2016. Epub 2016 Apr 20. Am J Physiol Cell Physiol. 2016. PMID: 27099349 Free article.

9

Intrasteric control of AMPK via the gamma1 subunit AMP allosteric regulatory site.

Adams J, Chen ZP, Van Denderen BJ, Morton CJ, Parker MW, Witters LA, Stapleton D, Kemp BE. Adams J, et al. Among authors: stapleton d. Protein Sci. 2004 Jan;13(1):155-65. doi: 10.1110/ps.03340004. Protein Sci. 2004. PMID: 14691231 Free PMC article.

10

AMP-activated protein kinase beta subunit tethers alpha and gamma subunits via its C-terminal sequence (186-270).

Iseli TJ, Walter M, van Denderen BJ, Katsis F, Witters LA, Kemp BE, Michell BJ, Stapleton D. Iseli TJ, et al. Among authors: stapleton d. J Biol Chem. 2005 Apr 8;280(14):13395-400. doi: 10.1074/jbc.M412993200. Epub 2005 Jan 28. J Biol Chem. 2005. PMID: 15695819 Free article.

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