Wang C - Search Results

1

Cyclic urea derivatives as potent NK1 selective antagonists. Part II: Effects of fluoro and benzylic methyl substitutions.

Shue HJ, Chen X, Schwerdt JH, Paliwal S, Blythin DJ, Lin L, Gu D, Wang C, Reichard GA, Wang H, Piwinski JJ, Duffy RA, Lachowicz JE, Coffin VL, Nomeir AA, Morgan CA, Varty GB, Shih NY. Shue HJ, et al. Among authors: wang h, wang c. Bioorg Med Chem Lett. 2006 Feb 15;16(4):1065-9. doi: 10.1016/j.bmcl.2005.10.072. Epub 2005 Nov 14. Bioorg Med Chem Lett. 2006. PMID: 16290143

2

Discovery of a novel, potent and orally active series of gamma-lactams as selective NK1 antagonists.

Paliwal S, Reichard GA, Shah S, Wrobleski ML, Wang C, Stengone C, Tsui HC, Xiao D, Duffy RA, Lachowicz JE, Nomeir AA, Varty GB, Shih NY. Paliwal S, et al. Among authors: wang c. Bioorg Med Chem Lett. 2008 Jul 15;18(14):4168-71. doi: 10.1016/j.bmcl.2008.05.082. Epub 2008 May 24. Bioorg Med Chem Lett. 2008. PMID: 18547807

3

Discovery of a series of potent, orally active α,α-disubstituted piperidine NK(1) antagonists.

Xiao D, Wang C, Palani A, Tsui HC, Reichard G, Paliwal S, Shih NY, Aslanian R, Duffy R, Lachowicz J, Varty G, Morgan C, Liu F, Nomeir A. Xiao D, et al. Among authors: wang c. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6313-5. doi: 10.1016/j.bmcl.2010.08.059. Epub 2010 Aug 15. Bioorg Med Chem Lett. 2010. PMID: 20846861

4

Asymmetric synthesis of 4,4-disubstituted-2-imidazoli-dinones: potent NK1 antagonists.

Reichard GA, Stengone C, Paliwal S, Mergelsberg I, Majmundar S, Wang C, Tiberi R, McPhail AT, Piwinski JJ, Shih NY. Reichard GA, et al. Among authors: wang c. Org Lett. 2003 Nov 13;5(23):4249-51. doi: 10.1021/ol030104p. Org Lett. 2003. PMID: 14601972

5

Synthesis and fluorescent study of 5-phenyl furocoumarin derivatives as vasodilatory agents.

Wang C, Wang T, Huang L, Lu W, Zhang J, He H. Wang C, et al. Among authors: wang t. Bioorg Med Chem Lett. 2016 Jan 15;26(2):640-644. doi: 10.1016/j.bmcl.2015.11.056. Epub 2015 Nov 17. Bioorg Med Chem Lett. 2016. PMID: 26627580

6

Highly Selective, Potent, and Oral mTOR Inhibitor for Treatment of Cancer as Autophagy Inducer.

Guo Q, Yu C, Zhang C, Li Y, Wang T, Huang Z, Wang X, Zhou W, Li Y, Qin Z, Wang C, Gao R, Nie Y, Ma Y, Shi Y, Zheng J, Yang S, Fan Y, Xiang R. Guo Q, et al. Among authors: wang x, wang t, wang c. J Med Chem. 2018 Feb 8;61(3):881-904. doi: 10.1021/acs.jmedchem.7b01402. Epub 2018 Jan 27. J Med Chem. 2018. PMID: 29308895

7

Pyridyl aminothiazoles as potent Chk1 inhibitors: optimization of cellular activity.

Dudkin VY, Wang C, Arrington KL, Fraley ME, Hartman GD, Stirdivant SM, Drakas RA, Rickert K, Walsh ES, Hamilton K, Buser CA, Hardwick J, Tao W, Beck SC, Mao X, Lobell RB, Sepp-Lorenzino L. Dudkin VY, et al. Among authors: wang c. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2613-9. doi: 10.1016/j.bmcl.2012.01.120. Epub 2012 Feb 7. Bioorg Med Chem Lett. 2012. PMID: 22365762

8

Pyridyl aminothiazoles as potent inhibitors of Chk1 with slow dissociation rates.

Dudkin VY, Rickert K, Kreatsoulas C, Wang C, Arrington KL, Fraley ME, Hartman GD, Yan Y, Ikuta M, Stirdivant SM, Drakas RA, Walsh ES, Hamilton K, Buser CA, Lobell RB, Sepp-Lorenzino L. Dudkin VY, et al. Among authors: wang c. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2609-12. doi: 10.1016/j.bmcl.2012.01.110. Epub 2012 Feb 9. Bioorg Med Chem Lett. 2012. PMID: 22374217

9

3D-QSAR-aided design, synthesis, in vitro and in vivo evaluation of dipeptidyl boronic acid proteasome inhibitors and mechanism studies.

Lei M, Feng H, Wang C, Li H, Shi J, Wang J, Liu Z, Chen S, Hu S, Zhu Y. Lei M, et al. Among authors: wang j, wang c. Bioorg Med Chem. 2016 Jun 1;24(11):2576-2588. doi: 10.1016/j.bmc.2016.04.025. Epub 2016 Apr 13. Bioorg Med Chem. 2016. PMID: 27117691

10

Design, synthesis, and evaluation of salicyladimine derivatives as multitarget-directed ligands against Alzheimer's disease.

Yang HL, Cai P, Liu QH, Yang XL, Fang SQ, Tang YW, Wang C, Wang XB, Kong LY. Yang HL, et al. Among authors: wang c, wang xb. Bioorg Med Chem. 2017 Nov 1;25(21):5917-5928. doi: 10.1016/j.bmc.2017.08.048. Epub 2017 Sep 27. Bioorg Med Chem. 2017. PMID: 28988627

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