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2-(Quinazolin-4-ylamino)-[1,4]benzoquinones as covalent-binding, irreversible inhibitors of the kinase domain of vascular endothelial growth factor receptor-2.
Wissner A, Floyd MB, Johnson BD, Fraser H, Ingalls C, Nittoli T, Dushin RG, Discafani C, Nilakantan R, Marini J, Ravi M, Cheung K, Tan X, Musto S, Annable T, Siegel MM, Loganzo F. Wissner A, et al. Among authors: fraser h. J Med Chem. 2005 Dec 1;48(24):7560-81. doi: 10.1021/jm050559f. J Med Chem. 2005. PMID: 16302797
Benzo[c][2,7]naphthyridines as inhibitors of PDK-1.
Kim KH, Wissner A, Floyd MB Jr, Fraser HL, Wang YD, Dushin RG, Hu Y, Olland A, Guo B, Arndt K. Kim KH, et al. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5225-8. doi: 10.1016/j.bmcl.2009.07.007. Epub 2009 Jul 8. Bioorg Med Chem Lett. 2009. PMID: 19628388
The identification of 8,9-dimethoxy-5-(2-aminoalkoxy-pyridin-3-yl)-benzo[c][2,7]naphthyridin-4-ylamines as potent inhibitors of 3-phosphoinositide-dependent kinase-1 (PDK-1).
Nittoli T, Dushin RG, Ingalls C, Cheung K, Floyd MB, Fraser H, Olland A, Hu Y, Grosu G, Han X, Arndt K, Guo B, Wissner A. Nittoli T, et al. Among authors: fraser h. Eur J Med Chem. 2010 Apr;45(4):1379-86. doi: 10.1016/j.ejmech.2009.12.036. Epub 2009 Dec 28. Eur J Med Chem. 2010. PMID: 20074837
Impact and cost-effectiveness of scaling up HCV testing and treatment strategies for achieving HCV elimination among people who inject drugs in England: a mathematical modelling study.
Ward Z, Simmons R, Fraser H, Trickey A, Kesten J, Gibson A, Reid L, Cox S, Gordon F, Mc Pherson S, Ryder S, Vilar J, Miners A, Williams J, Emmanouil B, Desai M, Coughlan L, Harris R, Foster GR, Hickman M, Mandal S, Vickerman P. Ward Z, et al. Among authors: fraser h. Lancet Reg Health Eur. 2024 Dec 12;49:101176. doi: 10.1016/j.lanepe.2024.101176. eCollection 2025 Feb. Lancet Reg Health Eur. 2024. PMID: 39759576 Free PMC article.
Predicting the replicability of social and behavioural science claims in COVID-19 preprints.
Marcoci A, Wilkinson DP, Vercammen A, Wintle BC, Abatayo AL, Baskin E, Berkman H, Buchanan EM, Capitán S, Capitán T, Chan G, Cheng KJG, Coupé T, Dryhurst S, Duan J, Edlund JE, Errington TM, Fedor A, Fidler F, Field JG, Fox N, Fraser H, Freeman ALJ, Hanea A, Holzmeister F, Hong S, Huggins R, Huntington-Klein N, Johannesson M, Jones AM, Kapoor H, Kerr J, Kline Struhl M, Kołczyńska M, Liu Y, Loomas Z, Luis B, Méndez E, Miske O, Mody F, Nast C, Nosek BA, Simon Parsons E, Pfeiffer T, Reed WR, Roozenbeek J, Schlyfestone AR, Schneider CR, Soh A, Song Z, Tagat A, Tutor M, Tyner AH, Urbanska K, van der Linden S. Marcoci A, et al. Among authors: fraser h. Nat Hum Behav. 2024 Dec 20. doi: 10.1038/s41562-024-01961-1. Online ahead of print. Nat Hum Behav. 2024. PMID: 39706868
Genetic modifiers and ascertainment drive variable expressivity of complex disorders.
Jensen M, Smolen C, Tyryshkina A, Pizzo L, Banerjee D, Oetjens M, Shimelis H, Taylor CM, Pounraja VK, Song H, Rohan L, Huber E, El Khattabi L, van de Laar I, Tadros R, Bezzina C, van Slegtenhorst M, Kammeraad J, Prontera P, Caberg JH, Fraser H, Banka S, Van Dijck A, Schwartz C, Voorhoeve E, Callier P, Mosca-Boidron AL, Marle N, Lefebvre M, Pope K, Snell P, Boys A, Lockhart PJ, Ashfaq M, McCready E, Nowacyzk M, Castiglia L, Galesi O, Avola E, Mattina T, Fichera M, Bruccheri MG, Mandarà GML, Mari F, Privitera F, Longo I, Curró A, Renieri A, Keren B, Charles P, Cuinat S, Nizon M, Pichon O, Bénéteau C, Stoeva R, Martin-Coignard D, Blesson S, Le Caignec C, Mercier S, Vincent M, Martin C, Mannik K, Reymond A, Faivre L, Sistermans E, Kooy RF, Amor DJ, Romano C, Andrieux J, Girirajan S. Jensen M, et al. Among authors: fraser h. medRxiv [Preprint]. 2024 Aug 28:2024.08.27.24312158. doi: 10.1101/2024.08.27.24312158. medRxiv. 2024. PMID: 39252907 Free PMC article. Preprint.
Baseline Characteristics in the Remote Diet Intervention to REduce long-COVID Symptoms Trial (ReDIRECT).
Haag L, Richardson J, Haig C, Cunningham Y, Fraser H, Brosnahan N, Ibbotson T, Ormerod J, White C, McIntosh E, O'Donnell K, Sattar N, McConnachie A, Lean M, Blane D, Combet E. Haag L, et al. Among authors: fraser h. NIHR Open Res. 2024 Mar 5;4:7. doi: 10.3310/nihropenres.13522.1. eCollection 2024. NIHR Open Res. 2024. PMID: 39145102 Free PMC article.
986 results