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Discovery of potent chromen-4-one inhibitors of the DNA-dependent protein kinase (DNA-PK) using a small-molecule library approach.
J Med Chem. 2005 Dec 1;48(24):7829-46. doi: 10.1021/jm050444b.
J Med Chem. 2005.
PMID: 16302822
Judicious application of allyl protecting groups for the synthesis of 2-morpholin-4-yl-4-oxo-4H-chromen-8-yl triflate, a key precursor of DNA-dependent protein kinase inhibitors.
Aristegui SR, El-Murr MD, Golding BT, Griffin RJ, Hardcastle IR.
Aristegui SR, et al. Among authors: el murr md.
Org Lett. 2006 Dec 21;8(26):5927-9. doi: 10.1021/ol062297x.
Org Lett. 2006.
PMID: 17165896
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