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Trans-arachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration.
Kermorvant-Duchemin E, Sennlaub F, Sirinyan M, Brault S, Andelfinger G, Kooli A, Germain S, Ong H, d'Orleans-Juste P, Gobeil F Jr, Zhu T, Boisvert C, Hardy P, Jain K, Falck JR, Balazy M, Chemtob S. Kermorvant-Duchemin E, et al. Nat Med. 2005 Dec;11(12):1339-45. doi: 10.1038/nm1336. Epub 2005 Nov 27. Nat Med. 2005. PMID: 16311602 Free PMC article.
Hypercapnia prevents neovascularization via nitrative stress.
Checchin D, Sennlaub F, Sirinyan M, Brault S, Zhu T, Kermorvant-Duchemin E, Hardy P, Balazy M, Chemtob S. Checchin D, et al. Free Radic Biol Med. 2006 Feb 1;40(3):543-53. doi: 10.1016/j.freeradbiomed.2005.09.016. Epub 2005 Nov 14. Free Radic Biol Med. 2006. PMID: 16443170
The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis.
Sapieha P, Sirinyan M, Hamel D, Zaniolo K, Joyal JS, Cho JH, Honoré JC, Kermorvant-Duchemin E, Varma DR, Tremblay S, Leduc M, Rihakova L, Hardy P, Klein WH, Mu X, Mamer O, Lachapelle P, Di Polo A, Beauséjour C, Andelfinger G, Mitchell G, Sennlaub F, Chemtob S. Sapieha P, et al. Nat Med. 2008 Oct;14(10):1067-76. doi: 10.1038/nm.1873. Epub 2008 Oct 5. Nat Med. 2008. PMID: 18836459
Cytotoxicity of the E(2)-isoprostane 15-E(2t)-IsoP on oligodendrocyte progenitors.
Brault S, Martinez-Bermudez AK, Roberts J 2nd, Cui QL, Fragoso G, Hemdan S, Liu HN, Gobeil F Jr, Quiniou C, Kermorvant-Duchemin E, Lachance C, Almazan G, Varma DR, Chemtob S. Brault S, et al. Free Radic Biol Med. 2004 Aug 1;37(3):358-66. doi: 10.1016/j.freeradbiomed.2004.05.007. Free Radic Biol Med. 2004. PMID: 15223069
Choroidal involution is a key component of oxygen-induced retinopathy.
Shao Z, Dorfman AL, Seshadri S, Djavari M, Kermorvant-Duchemin E, Sennlaub F, Blais M, Polosa A, Varma DR, Joyal JS, Lachapelle P, Hardy P, Sitaras N, Picard E, Mancini J, Sapieha P, Chemtob S. Shao Z, et al. Invest Ophthalmol Vis Sci. 2011 Aug 5;52(9):6238-48. doi: 10.1167/iovs.10-6742. Invest Ophthalmol Vis Sci. 2011. PMID: 21546530
77 results