Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic ras and tyrosine kinases.
Marais R, Light Y, Paterson HF, Mason CS, Marshall CJ.
Marais R, et al. Among authors: light y.
J Biol Chem. 1997 Feb 14;272(7):4378-83. doi: 10.1074/jbc.272.7.4378.
J Biol Chem. 1997.
PMID: 9020159
Free article.
This synergy arises because Ras-GTP translocates Raf-1 to the plasma membrane where it becomes phosphorylated on tyrosine residues 340 and 341 by membrane-bound tyrosine kinases (Marais, R., Light, Y., Paterson, H. F., and Marshall, C. J. (1995) EMBO J. 14, 3136-314 …
This synergy arises because Ras-GTP translocates Raf-1 to the plasma membrane where it becomes phosphorylated on tyrosine residues 340 and 3 …