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Page 1
Crystal structures of two bacterial 3-hydroxy-3-methylglutaryl-CoA lyases suggest a common catalytic mechanism among a family of TIM barrel metalloenzymes cleaving carbon-carbon bonds.
Forouhar F, Hussain M, Farid R, Benach J, Abashidze M, Edstrom WC, Vorobiev SM, Xiao R, Acton TB, Fu Z, Kim JJ, Miziorko HM, Montelione GT, Hunt JF. Forouhar F, et al. Among authors: vorobiev sm. J Biol Chem. 2006 Mar 17;281(11):7533-45. doi: 10.1074/jbc.M507996200. Epub 2005 Dec 5. J Biol Chem. 2006. PMID: 16330546 Free article.
Automated streak-seeding with micromachined silicon tools.
Georgiev A, Vorobiev S, Edstrom W, Song T, Laine A, Hunt J, Allen P. Georgiev A, et al. Acta Crystallogr D Biol Crystallogr. 2006 Sep;62(Pt 9):1039-45. doi: 10.1107/S0907444906023705. Epub 2006 Aug 19. Acta Crystallogr D Biol Crystallogr. 2006. PMID: 16929105
Molecular insights into substrate recognition and catalysis by tryptophan 2,3-dioxygenase.
Forouhar F, Anderson JL, Mowat CG, Vorobiev SM, Hussain A, Abashidze M, Bruckmann C, Thackray SJ, Seetharaman J, Tucker T, Xiao R, Ma LC, Zhao L, Acton TB, Montelione GT, Chapman SK, Tong L. Forouhar F, et al. Among authors: vorobiev sm. Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):473-8. doi: 10.1073/pnas.0610007104. Epub 2006 Dec 29. Proc Natl Acad Sci U S A. 2007. PMID: 17197414 Free PMC article.
Crystal structure of human retinoblastoma binding protein 9.
Vorobiev SM, Su M, Seetharaman J, Huang YJ, Chen CX, Maglaqui M, Janjua H, Proudfoot M, Yakunin A, Xiao R, Acton TB, Montelione GT, Tong L. Vorobiev SM, et al. Proteins. 2009 Feb 1;74(2):526-9. doi: 10.1002/prot.22278. Proteins. 2009. PMID: 19004028 Free PMC article. No abstract available.
Computational design of catalytic dyads and oxyanion holes for ester hydrolysis.
Richter F, Blomberg R, Khare SD, Kiss G, Kuzin AP, Smith AJ, Gallaher J, Pianowski Z, Helgeson RC, Grjasnow A, Xiao R, Seetharaman J, Su M, Vorobiev S, Lew S, Forouhar F, Kornhaber GJ, Hunt JF, Montelione GT, Tong L, Houk KN, Hilvert D, Baker D. Richter F, et al. J Am Chem Soc. 2012 Oct 3;134(39):16197-206. doi: 10.1021/ja3037367. Epub 2012 Sep 21. J Am Chem Soc. 2012. PMID: 22871159 Free PMC article.
26 results