Croft SL - Search Results

1

Antitrypanosomal, antileishmanial, and antimalarial activities of quaternary arylalkylammonium 2-amino-4-chlorophenyl phenyl sulfides, a new class of trypanothione reductase inhibitor, and of N-acyl derivatives of 2-amino-4-chlorophenyl phenyl sulfide.

Parveen S, Khan MO, Austin SE, Croft SL, Yardley V, Rock P, Douglas KT. Parveen S, et al. Among authors: croft sl. J Med Chem. 2005 Dec 15;48(25):8087-97. doi: 10.1021/jm050819t. J Med Chem. 2005. PMID: 16335933

2

Evaluation of azasterols as anti-parasitics.

Gros L, Lorente SO, Jimenez CJ, Yardley V, Rattray L, Wharton H, Little S, Croft SL, Ruiz-Perez LM, Gonzalez-Pacanowska D, Gilbert IH. Gros L, et al. Among authors: croft sl. J Med Chem. 2006 Oct 5;49(20):6094-103. doi: 10.1021/jm060290f. J Med Chem. 2006. PMID: 17004723

3

Antiprotozoal glutathione derivatives with flagellar membrane binding activity against T. brucei rhodesiense.

Daunes S, Yardley V, Croft SL, D'Silva C. Daunes S, et al. Among authors: croft sl. Bioorg Med Chem. 2017 Feb 15;25(4):1329-1340. doi: 10.1016/j.bmc.2016.12.016. Epub 2016 Dec 18. Bioorg Med Chem. 2017. PMID: 28131508

4

Phenothiazine inhibitors of trypanothione reductase as potential antitrypanosomal and antileishmanial drugs.

Chan C, Yin H, Garforth J, McKie JH, Jaouhari R, Speers P, Douglas KT, Rock PJ, Yardley V, Croft SL, Fairlamb AH. Chan C, et al. Among authors: croft sl. J Med Chem. 1998 Jan 15;41(2):148-56. doi: 10.1021/jm960814j. J Med Chem. 1998. PMID: 9457238

5

Cytotoxicity of (2,2':6',2''-terpyridine)platinum(II) complexes to Leishmania donovani, Trypanosoma cruzi, and Trypanosoma brucei.

Lowe G, Droz AS, Vilaivan T, Weaver GW, Tweedale L, Pratt JM, Rock P, Yardley V, Croft SL. Lowe G, et al. Among authors: croft sl. J Med Chem. 1999 Mar 25;42(6):999-1006. doi: 10.1021/jm981074c. J Med Chem. 1999. PMID: 10090783

6

Use of an additional hydrophobic binding site, the Z site, in the rational drug design of a new class of stronger trypanothione reductase inhibitor, quaternary alkylammonium phenothiazines.

Khan MO, Austin SE, Chan C, Yin H, Marks D, Vaghjiani SN, Kendrick H, Yardley V, Croft SL, Douglas KT. Khan MO, et al. Among authors: croft sl. J Med Chem. 2000 Aug 10;43(16):3148-56. doi: 10.1021/jm000156+. J Med Chem. 2000. PMID: 10956223

7

QSAR study on the contribution of log P and E(s) to the in vitro antiprotozoal activity of glutathione derivatives.

Daunes S, D'Silva C, Kendrick H, Yardley V, Croft SL. Daunes S, et al. Among authors: croft sl. J Med Chem. 2001 Aug 30;44(18):2976-83. doi: 10.1021/jm000502n. J Med Chem. 2001. PMID: 11520206

8

2,4-Diaminopyrimidines as inhibitors of Leishmanial and Trypanosomal dihydrofolate reductase.

Pez D, Leal I, Zuccotto F, Boussard C, Brun R, Croft SL, Yardley V, Ruiz Perez LM, Gonzalez Pacanowska D, Gilbert IH. Pez D, et al. Among authors: croft sl. Bioorg Med Chem. 2003 Nov 3;11(22):4693-711. doi: 10.1016/j.bmc.2003.08.012. Bioorg Med Chem. 2003. PMID: 14556785

9

Azasterols as inhibitors of sterol 24-methyltransferase in Leishmania species and Trypanosoma cruzi.

Magaraci F, Jimenez CJ, Rodrigues C, Rodrigues JC, Braga MV, Yardley V, de Luca-Fradley K, Croft SL, de Souza W, Ruiz-Perez LM, Urbina J, Gonzalez Pacanowska D, Gilbert IH. Magaraci F, et al. Among authors: croft sl. J Med Chem. 2003 Oct 23;46(22):4714-27. doi: 10.1021/jm021114j. J Med Chem. 2003. PMID: 14561091

10

Synthesis and in vitro anti-protozoal activity of a series of benzotropolone derivatives incorporating endocyclic hydrazines.

Ren H, Grady S, Banghart M, Moulthrop JS, Kendrick H, Yardley V, Croft SL, Moyna G. Ren H, et al. Among authors: croft sl. Eur J Med Chem. 2003 Nov-Dec;38(11-12):949-57. doi: 10.1016/j.ejmech.2003.07.004. Eur J Med Chem. 2003. PMID: 14642327

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