Mi S - Search Results

1

Disulfide structure of the leucine-rich repeat C-terminal cap and C-terminal stalk region of Nogo-66 receptor.

Wen D, Wildes CP, Silvian L, Walus L, Mi S, Lee DH, Meier W, Pepinsky RB. Wen D, et al. Among authors: mi s. Biochemistry. 2005 Dec 20;44(50):16491-501. doi: 10.1021/bi0517483. Biochemistry. 2005. PMID: 16342940

2

LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex.

Mi S, Lee X, Shao Z, Thill G, Ji B, Relton J, Levesque M, Allaire N, Perrin S, Sands B, Crowell T, Cate RL, McCoy JM, Pepinsky RB. Mi S, et al. Nat Neurosci. 2004 Mar;7(3):221-8. doi: 10.1038/nn1188. Epub 2004 Feb 15. Nat Neurosci. 2004. PMID: 14966521

3

Characterization of trisulfide modification in antibodies.

Gu S, Wen D, Weinreb PH, Sun Y, Zhang L, Foley SF, Kshirsagar R, Evans D, Mi S, Meier W, Pepinsky RB. Gu S, et al. Among authors: mi s. Anal Biochem. 2010 May 1;400(1):89-98. doi: 10.1016/j.ab.2010.01.019. Epub 2010 Jan 18. Anal Biochem. 2010. PMID: 20085742

4

Improving the solubility of anti-LINGO-1 monoclonal antibody Li33 by isotype switching and targeted mutagenesis.

Pepinsky RB, Silvian L, Berkowitz SA, Farrington G, Lugovskoy A, Walus L, Eldredge J, Capili A, Mi S, Graff C, Garber E. Pepinsky RB, et al. Among authors: mi s. Protein Sci. 2010 May;19(5):954-66. doi: 10.1002/pro.372. Protein Sci. 2010. PMID: 20198683 Free PMC article.

5

TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration.

Shao Z, Browning JL, Lee X, Scott ML, Shulga-Morskaya S, Allaire N, Thill G, Levesque M, Sah D, McCoy JM, Murray B, Jung V, Pepinsky RB, Mi S. Shao Z, et al. Among authors: mi s. Neuron. 2005 Feb 3;45(3):353-9. doi: 10.1016/j.neuron.2004.12.050. Neuron. 2005. PMID: 15694322 Free article.

6

Exposure levels of anti-LINGO-1 Li81 antibody in the central nervous system and dose-efficacy relationships in rat spinal cord remyelination models after systemic administration.

Pepinsky RB, Shao Z, Ji B, Wang Q, Meng G, Walus L, Lee X, Hu Y, Graff C, Garber E, Meier W, Mi S. Pepinsky RB, et al. Among authors: mi s. J Pharmacol Exp Ther. 2011 Nov;339(2):519-29. doi: 10.1124/jpet.111.183483. Epub 2011 Aug 1. J Pharmacol Exp Ther. 2011. PMID: 21807883

7

Blocking LINGO-1 as a therapy to promote CNS repair: from concept to the clinic.

Mi S, Pepinsky RB, Cadavid D. Mi S, et al. CNS Drugs. 2013 Jul;27(7):493-503. doi: 10.1007/s40263-013-0068-8. CNS Drugs. 2013. PMID: 23681979 Review.

8

Production of a PEGylated Fab' of the anti-LINGO-1 Li33 antibody and assessment of its biochemical and functional properties in vitro and in a rat model of remyelination.

Pepinsky RB, Walus L, Shao Z, Ji B, Gu S, Sun Y, Wen D, Lee X, Wang Q, Garber E, Mi S. Pepinsky RB, et al. Among authors: mi s. Bioconjug Chem. 2011 Feb 16;22(2):200-10. doi: 10.1021/bc1002746. Epub 2011 Jan 21. Bioconjug Chem. 2011. PMID: 21254764

9

Death receptor 6 negatively regulates oligodendrocyte survival, maturation and myelination.

Mi S, Lee X, Hu Y, Ji B, Shao Z, Yang W, Huang G, Walus L, Rhodes K, Gong BJ, Miller RH, Pepinsky RB. Mi S, et al. Nat Med. 2011 Jul 3;17(7):816-21. doi: 10.1038/nm.2373. Nat Med. 2011. PMID: 21725297

10

Structure of the LINGO-1-anti-LINGO-1 Li81 antibody complex provides insights into the biology of LINGO-1 and the mechanism of action of the antibody therapy.

Pepinsky RB, Arndt JW, Quan C, Gao Y, Quintero-Monzon O, Lee X, Mi S. Pepinsky RB, et al. Among authors: mi s. J Pharmacol Exp Ther. 2014 Jul;350(1):110-23. doi: 10.1124/jpet.113.211771. Epub 2014 Apr 22. J Pharmacol Exp Ther. 2014. PMID: 24756303

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