Todhunter DA - Search Results

1

Intracranial therapy of glioblastoma with the fusion protein DTIL13 in immunodeficient mice.

Rustamzadeh E, Hall WA, Todhunter DA, Low WC, Liu H, Panoskaltsis-Mortari A, Vallera DA. Rustamzadeh E, et al. Among authors: todhunter da. Int J Cancer. 2006 May 15;118(10):2594-601. doi: 10.1002/ijc.21647. Int J Cancer. 2006. PMID: 16358262

2

Targeting glioblastoma multiforme with an IL-13/diphtheria toxin fusion protein in vitro and in vivo in nude mice.

Li C, Hall WA, Jin N, Todhunter DA, Panoskaltsis-Mortari A, Vallera DA. Li C, et al. Among authors: todhunter da. Protein Eng. 2002 May;15(5):419-27. doi: 10.1093/protein/15.5.419. Protein Eng. 2002. PMID: 12034862

3

A bispecific immunotoxin (DTAT13) targeting human IL-13 receptor (IL-13R) and urokinase-type plasminogen activator receptor (uPAR) in a mouse xenograft model.

Todhunter DA, Hall WA, Rustamzadeh E, Shu Y, Doumbia SO, Vallera DA. Todhunter DA, et al. Protein Eng Des Sel. 2004 Feb;17(2):157-64. doi: 10.1093/protein/gzh023. Epub 2004 Feb 13. Protein Eng Des Sel. 2004. PMID: 15047912

4

Molecular modification of a recombinant, bivalent anti-human CD3 immunotoxin (Bic3) results in reduced in vivo toxicity in mice.

Vallera DA, Todhunter D, Kuroki DW, Shu Y, Sicheneder A, Panoskaltsis-Mortari A, Vallera VD, Chen H. Vallera DA, et al. Among authors: todhunter d. Leuk Res. 2005 Mar;29(3):331-41. doi: 10.1016/j.leukres.2004.08.006. Leuk Res. 2005. PMID: 15661270

5

A bispecific recombinant immunotoxin, DT2219, targeting human CD19 and CD22 receptors in a mouse xenograft model of B-cell leukemia/lymphoma.

Vallera DA, Todhunter DA, Kuroki DW, Shu Y, Sicheneder A, Chen H. Vallera DA, et al. Among authors: todhunter da. Clin Cancer Res. 2005 May 15;11(10):3879-88. doi: 10.1158/1078-0432.CCR-04-2290. Clin Cancer Res. 2005. PMID: 15897589

6

Immunotoxin pharmacokinetics: a comparison of the anti-glioblastoma bi-specific fusion protein (DTAT13) to DTAT and DTIL13.

Rustamzadeh E, Vallera DA, Todhunter DA, Low WC, Panoskaltsis-Mortari A, Hall WA. Rustamzadeh E, et al. Among authors: todhunter da. J Neurooncol. 2006 May;77(3):257-66. doi: 10.1007/s11060-005-9051-7. J Neurooncol. 2006. PMID: 16314943

7

Intracranial therapy of glioblastoma with the fusion protein DTAT in immunodeficient mice.

Rustamzadeh E, Hall WA, Todhunter DA, Vallera VD, Low WC, Liu H, Panoskaltsis-Mortari A, Vallera DA. Rustamzadeh E, et al. Among authors: todhunter da. Int J Cancer. 2007 Jan 15;120(2):411-9. doi: 10.1002/ijc.22278. Int J Cancer. 2007. PMID: 17075792

8

Intracranial elimination of human glioblastoma brain tumors in nude rats using the bispecific ligand-directed toxin, DTEGF13 and convection enhanced delivery.

Oh S, Ohlfest JR, Todhunter DA, Vallera VD, Hall WA, Chen H, Vallera DA. Oh S, et al. Among authors: todhunter da. J Neurooncol. 2009 Dec;95(3):331-342. doi: 10.1007/s11060-009-9932-2. Epub 2009 Jun 11. J Neurooncol. 2009. PMID: 19517064

9

A deimmunized bispecific ligand-directed toxin that shows an impressive anti-pancreatic cancer effect in a systemic nude mouse orthotopic model.

Oh S, Todhunter DA, Panoskaltsis-Mortari A, Buchsbaum DJ, Toma S, Vallera DA. Oh S, et al. Among authors: todhunter da. Pancreas. 2012 Jul;41(5):789-96. doi: 10.1097/MPA.0b013e31823b5f2e. Pancreas. 2012. PMID: 22258068 Free PMC article.

10

Bispecific and trispecific killer cell engagers directly activate human NK cells through CD16 signaling and induce cytotoxicity and cytokine production.

Gleason MK, Verneris MR, Todhunter DA, Zhang B, McCullar V, Zhou SX, Panoskaltsis-Mortari A, Weiner LM, Vallera DA, Miller JS. Gleason MK, et al. Among authors: todhunter da. Mol Cancer Ther. 2012 Dec;11(12):2674-84. doi: 10.1158/1535-7163.MCT-12-0692. Epub 2012 Oct 17. Mol Cancer Ther. 2012. PMID: 23075808 Free PMC article.

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